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Literature DB >> 11029389

Immunological tolerance to inhaled antigen.

G F Hoyne¹, K Tan, M Corsin-Jimenez, K Wahl, M Stewart, S E Howie, J R Lamb.

Abstract

Regulatory mechanisms exist in the immune system to limit the induction of pathogenic responses to antigens encountered within the respiratory tract. The development of allergic disease is thought to arise as a result of the breakdown in these regulatory processes. In this review we examine the nature of immune responses generated to inhaled protein antigens and the mechanisms used to establish tolerance to inhaled antigens.

Entities: Disease

Mesh：

Substances：
Antigens

Year: 2000 PMID： 11029389 DOI： 10.1164/ajrccm.162.supplement_3.15tac6

Source DB: PubMed Journal: Am J Respir Crit Care Med ISSN： 1073-449X Impact factor: 21.405

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Cited

9 in total

1. Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation.

Authors: Edmund O'Brien; Page C Spiess; Aida Habibovic; Milena Hristova; Robert A Bauer; Matthew J Randall; Matthew E Poynter; Albert van der Vliet
Journal: J Immunotoxicol Date: 2015-04-15 Impact factor: 3.000

2. An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation.

Authors: S Hutchison; B S W Choo-Kang; V B Gibson; R V Bundick; A J Leishman; J M Brewer; I B McInnes; P Garside
Journal: Clin Exp Immunol Date: 2009-01 Impact factor: 4.330

Review 9. Cloned Defective Interfering Influenza RNA and a Possible Pan-Specific Treatment of Respiratory Virus Diseases.

Authors: Nigel J Dimmock; Andrew J Easton
Journal: Viruses Date: 2015-07-08 Impact factor: 5.048

9 in total

Immunological tolerance to inhaled antigen.

1. Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation.

2. An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation.

3. Are we getting enough allergens?

Review 4. Immunological mechanisms for desensitization and tolerance in food allergy.

Review 5. Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma.

6. Immune System as a Sensory System.

7. Neuroimmune semaphorin 4A downregulates the severity of allergic response.

8. Cigarette smoke exposure facilitates allergic sensitization in mice.

Review 9. Cloned Defective Interfering Influenza RNA and a Possible Pan-Specific Treatment of Respiratory Virus Diseases.