Literature DB >> 11029219

N-Benzylhydroxylamine addition to beta-aryl enoates. Enantioselective synthesis of beta-aryl-beta-amino acid precursors

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Abstract

Chiral Lewis acid catalyzed N-benzylhydroxylamine addition to pyrrolidinone-derived enoates afforded beta-aryl-beta-amino acid derivatives in high enantiomeric purity with moderate to very good chemical efficiency.

Entities:  

Year:  2000        PMID： 11029219     DOI： 10.1021/ol006500e

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Quantum mechanical investigation of the effect of catalyst fluorination in the intermolecular asymmetric Stetter reaction.

Authors:  Joann M Um; Daniel A DiRocco; Elizabeth L Noey; Tomislav Rovis; K N Houk
Journal:  J Am Chem Soc       Date:  2011-07-06       Impact factor: 15.419

2.  The Catalytic Asymmetric Intramolecular Stetter Reaction.

Authors:  Javier Read de Alaniz; Tomislav Rovis
Journal:  Synlett       Date:  2009-05       Impact factor: 2.454

3.  Enantio- and diastereoselective intermolecular Stetter reaction of glyoxamide and alkylidene ketoamides.

Authors:  Qin Liu; Tomislav Rovis
Journal:  Org Lett       Date:  2009-07-02       Impact factor: 6.005

4.  An expeditious synthesis of [1,2]isoxazolidin-5-ones and [1,2]oxazin-6-ones from functional allyl bromide derivatives.

Authors:  Imen Beltaïef; Aïcha Arfaoui; Hassen Amri
Journal:  Molecules       Date:  2010-06-07       Impact factor: 4.411
  4 in total

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