Literature DB >> 1102877

A controlled trial of maprotiline (Ludiomil) in depressed outpatients.

P McCallum, R Meares.   

Abstract

A double blind comparison is reported of a new tetracyclic antidepressant, maprotiline, with amitriptyline and placebo in psychiatric outpatients. Amitriptyline was significantly more effective than placebo in its global effect on depression. Maprotiline emerged as neither inferior to amitriptyline nor superior to placebo. Methodological difficulties prevented an adequate assessment of the anxiolytic activity of maprotiline.

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Year:  1975        PMID: 1102877     DOI: 10.5694/j.1326-5377.1975.tb105901.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  3 in total

1.  A comparison of antidepressant trials using active and inert placebos.

Authors:  Joanna Moncrieff
Journal:  Int J Methods Psychiatr Res       Date:  2003       Impact factor: 4.035

Review 2.  Maprotiline: a review of its pharmacological properties and therapeutic efficacy in mental depressive states.

Authors:  R M Pinder; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1977-05       Impact factor: 9.546

3.  Placebo-controlled trial of mianserin and maprotiline in primary depressive illness: a preliminary report.

Authors:  J G Edwards; A Goldie
Journal:  Br J Clin Pharmacol       Date:  1983       Impact factor: 4.335

  3 in total

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