PURPOSE: To describe an ocular complication of rifabutin therapy in the treatment of Mycobacterium avium complex (MAC) infection in the absence of HIV infection or AIDS. METHODS: Three patients on rifabutin therapy for MAC chest infection developed anterior uveitis with vitreous infiltrates. The clinical course and visual outcome are discussed. RESULTS: The ocular signs of anterior segment inflammation along with vitreous infiltrate resolved on topical steroid therapy without long-term visual sequelae. CONCLUSION: This report highlights the potential of uveitis in patients treated for MAC infection with rifabutin without concurrent HIV infection or AIDS.
PURPOSE: To describe an ocular complication of rifabutin therapy in the treatment of Mycobacterium avium complex (MAC) infection in the absence of HIV infection or AIDS. METHODS: Three patients on rifabutin therapy for MACchest infection developed anterior uveitis with vitreous infiltrates. The clinical course and visual outcome are discussed. RESULTS: The ocular signs of anterior segment inflammation along with vitreous infiltrate resolved on topical steroid therapy without long-term visual sequelae. CONCLUSION: This report highlights the potential of uveitis in patients treated for MAC infection with rifabutin without concurrent HIV infection or AIDS.
Authors: Matt Mason; Eric Gregory; Keith Foster; Megan Klatt; Sara Zoubek; Albert J Eid Journal: Open Forum Infect Dis Date: 2022-06-15 Impact factor: 4.423