Literature DB >> 11025148

Antiplasmodial activity of isoflavones from Andira inermis.

C Kraft1, K Jenett-Siems, K Siems, M P Gupta, U Bienzle, E Eich.   

Abstract

The stem bark and seeds of Andira inermis, Fabaceae, are employed as a purgative, vermifuge, and febrifuge. In particular, the powdered bark is claimed to be efficacious in intermittent fever. Bioassay-guided fractionation of lipophilic extracts from the stems and leaves yielded six isoflavones: biochanin A, calycosin, formononetin, genistein, pratensein, and prunetin. Calycosin (3', 7-dihydroxy-4'-methoxyisoflavone) and genistein (4',5, 7-trihydroxyisoflavone) have been shown to possess in vitro activity against the chloroquine-sensitive strain poW and the chloroquine-resistant clone Dd2 of Plasmodium falciparum.

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Year:  2000        PMID： 11025148     DOI： 10.1016/s0378-8741(00)00285-3

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  8 in total

1.  Antiplasmodial activity of flavonol quercetin and its analogues in Plasmodium falciparum: evidence from clinical isolates in Bangladesh and standardized parasite clones.

Authors:  Deepa Ganesh; Hans-Peter Fuehrer; Peter Starzengrüber; Paul Swoboda; Wasif Ali Khan; Johannes A B Reismann; Milena S K Mueller; Peter Chiba; Harald Noedl
Journal:  Parasitol Res       Date:  2012-01-04       Impact factor: 2.289

2.  In vitro metacestodicidal activities of genistein and other isoflavones against Echinococcus multilocularis and Echinococcus granulosus.

Authors:  Arunasalam Naguleswaran; Martin Spicher; Nathalie Vonlaufen; Luis M Ortega-Mora; Paul Torgerson; Bruno Gottstein; Andrew Hemphill
Journal:  Antimicrob Agents Chemother       Date:  2006-09-05       Impact factor: 5.191

3.  In vitro antiplasmodial activity of crude extracts of Tetrapleura tetraptera and Copaifera religiosa.

Authors:  Jean Bernard Lekana-Douki; Sandrine Lydie Oyegue Liabagui; Jean Bernard Bongui; Rafika Zatra; Jacques Lebibi; Fousseyni S Toure-Ndouo
Journal:  BMC Res Notes       Date:  2011-11-23

Review 4.  Formononetin: A Review of Its Anticancer Potentials and Mechanisms.

Authors:  Kai-Ching Tay; Loh Teng-Hern Tan; Chim Kei Chan; Sok Lai Hong; Kok-Gan Chan; Wei Hsum Yap; Priyia Pusparajah; Learn-Han Lee; Bey-Hing Goh
Journal:  Front Pharmacol       Date:  2019-07-26       Impact factor: 5.810

5.  Cytotoxycity and antiplasmodial activity of phenolic derivatives from Albizia zygia (DC.) J.F. Macbr. (Mimosaceae).

Authors:  Romeol Romain Koagne; Frederick Annang; Bastien Cautain; Jesús Martín; Guiomar Pérez-Moreno; Gabin Thierry M Bitchagno; Dolores González-Pacanowska; Francisca Vicente; Ingrid Konga Simo; Fernando Reyes; Pierre Tane
Journal:  BMC Complement Med Ther       Date:  2020-01-15

6.  Genistein-supplemented diet decreases malaria liver infection in mice and constitutes a potential prophylactic strategy.

Authors:  Margarida Cunha-Rodrigues; Sílvia Portugal; Miguel Prudêncio; Lígia A Gonçalves; Cristina Casalou; Dominik Buger; Robert Sauerwein; Werner Haas; Maria M Mota
Journal:  PLoS One       Date:  2008-07-16       Impact factor: 3.240

7.  Common dietary flavonoids inhibit the growth of the intraerythrocytic malaria parasite.

Authors:  Adele M Lehane; Kevin J Saliba
Journal:  BMC Res Notes       Date:  2008-06-18

8.  Effects of the vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor SU5416 on in vitro cultures of Plasmodium falciparum.

Authors:  Casper Hempel; Nils Hoyer; Trine Staalsø; Jørgen A Kurtzhals
Journal:  Malar J       Date:  2014-05-28       Impact factor: 2.979
  8 in total

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