| Literature DB >> 11025145 |
H F Smit1, B H Kroes, A J van den Berg, D van der Wal, E van den Worm, C J Beukelman, H van Dijk, R P Labadie.
Abstract
Extracts of the rhizomes of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae) were investigated for their in vitro and in vivo immunomodulatory properties. Diethyl ether extracts showed potent inhibitory activity towards the classical pathway of the complement system, the respiratory burst of activated polymorphonuclear leukocytes, and mitogen-induced proliferation of T-lymphocytes. Furthermore, such extracts showed anti-inflammatory activity towards carrageenan-induced paw edema. No effects were observed in experimentally induced arthritis in mice.Entities:
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Year: 2000 PMID： 11025145 DOI： 10.1016/s0378-8741(00)00268-3
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360