Literature DB >> 11024427

Chronic exposure keratopathy complicating surgical correction of ptosis in patients with chronic progressive external ophthalmoplegia.

P M Daut1, T L Steinemann, C T Westfall.   

Abstract

PURPOSE: To report chronic exposure keratopathy related to surgical ptosis correction in patients with chronic, progressive, external ophthalmoplegia.
METHODS: Case reports of three patients with chronic exposure keratopathy following blepharoptosis surgery.
RESULTS: We report three patients with chronic progressive external ophthalmoplegia with chronic corneal complications after surgical ptosis repair. All three gave a history of blepharoptosis and extraocular muscle dysfunction. Each presented with chronic corneal ulceration. All had histories suggestive of ophthalmoplegia. Treatment of corneal ulceration necessitated hospitalization and surgical intervention.
CONCLUSION: Patients with chronic, progressive, external ophthalmoplegia have little ability to properly protect the eye from exposure and are at risk for corneal damage. A thorough ophthalmic history and examination before ptosis surgery may prevent the corneal complications resulting from surgical intervention.

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Year:  2000        PMID: 11024427     DOI: 10.1016/s0002-9394(00)00558-4

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  6 in total

Review 1.  Chronic progressive external ophthalmoplegia.

Authors:  Andrew G Lee; Paul W Brazis
Journal:  Curr Neurol Neurosci Rep       Date:  2002-09       Impact factor: 5.081

2.  Mitochondrial myopathy presenting with segmental corneal oedema and retrocorneal membrane.

Authors:  Marcus H Colyer; Kraig S Bower; Thomas P Ward; Ahmad A Hidayat; Prem S Subramanian
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Review 3.  The neuro-ophthalmology of mitochondrial disease.

Authors:  J Alexander Fraser; Valérie Biousse; Nancy J Newman
Journal:  Surv Ophthalmol       Date:  2010-05-14       Impact factor: 6.048

Review 4.  Mitochondrial disorders of DNA polymerase γ dysfunction: from anatomic to molecular pathology diagnosis.

Authors:  Linsheng Zhang; Sherine S L Chan; Daynna J Wolff
Journal:  Arch Pathol Lab Med       Date:  2011-07       Impact factor: 5.534

Review 5.  Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.

Authors:  Patrick Yu-Wai-Man; Philip G Griffiths; Patrick F Chinnery
Journal:  Prog Retin Eye Res       Date:  2010-11-26       Impact factor: 21.198

6.  Bilateral lid/brow elevation procedure for severe ptosis in Kearns-Sayre syndrome, a mitochondrial cytopathy.

Authors:  Roberto Sebastiá; Ester Fallico; Matteo Fallico; Eduardo Fortuna; Sergio Lessa; Guilherme Herzog Neto
Journal:  Clin Ophthalmol       Date:  2014-12-22
  6 in total

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