Literature DB >> 11023342

Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans.

L J Lesko1, M Rowland, C C Peck, T F Blaschke, D Breimer, H J de Jong, A Grahnen, J J Kuhlmann, B Stewart.   

Abstract

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Year:  2000        PMID： 11023342     DOI： 10.1016/s0928-0987(00)00092-0

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN： 0928-0987            Impact factor:   4.384


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  7 in total

Review 1.  Concentration-controlled or effect-controlled trials: useful alternatives to conventional dose-controlled trials?

Authors:  A Grahnén; M O Karlsson
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

Review 2.  Utilisation of pharmacokinetic-pharmacodynamic modelling and simulation in regulatory decision-making.

Authors:  J V Gobburu; P J Marroum
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

3.  Modeling and stimulation for clinical trial design involving a categorical response: a phase II case study with naratriptan.

Authors:  I Nestorov; G Graham; S Duffull; L Aarons; E Fuseau; P Coates
Journal:  Pharm Res       Date:  2001-08       Impact factor: 4.200

4.  Getting the Dose Right: report from the Tenth European Federation of Pharmaceutical Sciences (EUFEPS) conference on optimizing drug development.

Authors:  Donald R Stanski; Malcolm Rowland; Lewis B Sheiner
Journal:  J Pharmacokinet Pharmacodyn       Date:  2005-11-07       Impact factor: 2.745

5.  Uncertainty analysis in pharmacokinetics and pharmacodynamics: application to naratriptan.

Authors:  Ivelina Gueorguieva; Ivan A Nestorov; Leon Aarons; Malcolm Rowland
Journal:  Pharm Res       Date:  2005-09-22       Impact factor: 4.200

Review 6.  Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trials.

Authors:  Joe N Kornegay; Christopher F Spurney; Peter P Nghiem; Candice L Brinkmeyer-Langford; Eric P Hoffman; Kanneboyina Nagaraju
Journal:  ILAR J       Date:  2014

Review 7.  Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development.

Authors:  Mats Bergström; Anders Grahnén; Bengt Långström
Journal:  Eur J Clin Pharmacol       Date:  2003-08-22       Impact factor: 2.953
  7 in total

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