Literature DB >> 11022912

A multi-element ICP-MS survey method as an alternative to the heavy metals limit test for pharmaceutical materials.

T Wang1, J Wu, R Hartman, X Jia, R S Egan.   

Abstract

A multi-element inductively coupled plasma-mass spectrometry (ICP-MS) survey method has been demonstrated as an alternative to the antiquated 'heavy metals limit test' prescribed by United States Pharmacopoeia (USP), European Pharmacopoeia (EP), and British Pharmacopoeia (BP), for drug substances, intermediates, and raw materials. The survey method is simple, fast, sensitive, semi-quantitative to quantitative, and includes all the elements which can be analyzed by atomic spectroscopy.

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Year:  2000        PMID: 11022912     DOI: 10.1016/s0731-7085(00)00361-7

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  2 in total

Review 1.  Metal impurities in food and drugs.

Authors:  Darrell R Abernethy; Anthony J Destefano; Todd L Cecil; Kahkashan Zaidi; Roger L Williams
Journal:  Pharm Res       Date:  2010-03-09       Impact factor: 4.200

2.  Instrumental neutron activation analysis (INAA) and liquid chromatography (LC) coupled to high resolution mass spectrometry (HRMS) characterisation of sildenafil based products seized on the Italian illegal market.

Authors:  Francesco Saverio Romolo; Andrea Salvini; Fabio Zelaschi; Massimo Oddone; Sara Odoardi; Serena Mestria; Sabina Strano Rossi
Journal:  Forensic Sci Int       Date:  2019-07-20       Impact factor: 2.395

  2 in total

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