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Literature DB >> 1101916

Kinetic studies of circulating lymphocytes in malignant lymphatic disease using the impulse cytophotometer.

F J Cleton, L A Smets, H Van Rooy, A M Boogaards.

Abstract

Measurements of the DNA content of mononuclear cells in the blood of patients with malignant lymphatic disease were made. In one case of acute lymphoblastic leukaemia, a large fraction of large type of blasts were in S phase. In the blood of a patient with leukaemic transformation of lymphosarcoma, a population of aneuploid tumour cells with a high percentage of cells in S phase was recognized. The increase of DNA synthesizing cells in the blood of patients with malignant lymphoma was associated with activity of the disease. The fraction of DNA synthesizing cells was raised sharply during chemotherapy.

Entities: Disease Species

Mesh：

Substances：

Year: 1975 PMID： 1101916 PMCID： PMC2149600

Source DB: PubMed Journal: Br J Cancer Suppl ISSN： 0306-9443

9 in total

1. Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes.

Authors: K M Matchett; A T Huang; W B Kremer
Journal: J Clin Invest Date: 1973-08 Impact factor: 14.808

Review 2. The role of immunoblasts in host resistance and immunotherapy of primary sarcomata.

Authors: P Alexander; J G Hall
Journal: Adv Cancer Res Date: 1970 Impact factor: 6.242

3. Separation of viable from nonviable tumor cells by flotation on a Ficoll-Triosil mixture.

Authors: J E de Vries; M van Benthem; P Rümke
Journal: Transplantation Date: 1973-04 Impact factor: 4.939

4. The selective elimination of immunologically competent cells from bone marrow and lymphatic cell mixtures. II. Mouse spleen cell fractionation on a discontinuous albumin gradient.

Authors: J I van Dicke KA Hooft; D W van Bekkum
Journal: Transplantation Date: 1968-07 Impact factor: 4.939

2 in total

1. Spontaneous lymphocyte transformation in relation to the number of circulating lymphocytes in Hodgkin's disease.

Authors: P H de Mulder; B E de Pauw; D J Wagener; C Haanen
Journal: Blut Date: 1981-04

2. Early responses to chemotherapy detected by pulse cytophotometry.

Authors: L A Smets; E Mulder; F C de Waal; F J Cleton; J Blok
Journal: Br J Cancer Date: 1976-08 Impact factor: 7.640

2 in total

Kinetic studies of circulating lymphocytes in malignant lymphatic disease using the impulse cytophotometer.

1. Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes.

Review 2. The role of immunoblasts in host resistance and immunotherapy of primary sarcomata.

3. Separation of viable from nonviable tumor cells by flotation on a Ficoll-Triosil mixture.

4. The selective elimination of immunologically competent cells from bone marrow and lymphatic cell mixtures. II. Mouse spleen cell fractionation on a discontinuous albumin gradient.

5. The thoracic duct lymph in Hodgkin's disease. II. Quantitative analysis of the cellular composition of the lymph.

6. Significance of the changes in the circulating lymphoid cells in Hodgkin's disease.

7. [DNA-synthesis in blood lymphocytes in malignant lymphogranuloma].

8. Cell population kinetics in human acute leukaemia.

9. Observations on abnormal cells in the peripheral blood and spleen in Hodgkin's disease.

1. Spontaneous lymphocyte transformation in relation to the number of circulating lymphocytes in Hodgkin's disease.

2. Early responses to chemotherapy detected by pulse cytophotometry.