Literature DB >> 110186

The effects in vivo and in vitro of oxidative damage to purified alpha1-antitrypsin and to the enzyme-inhibiting activity of plasma.

A B Cohen.   

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Year:  1979        PMID: 110186     DOI: 10.1164/arrd.1979.119.6.953

Source DB:  PubMed          Journal:  Am Rev Respir Dis        ISSN: 0003-0805


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  17 in total

1.  Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase.

Authors:  R C Hubbard; F Ogushi; G A Fells; A M Cantin; S Jallat; M Courtney; R G Crystal
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

Review 2.  Utility of serologic testing in the diagnosis of noninfectious pulmonary disorders.

Authors:  R H White; J A Golden
Journal:  Clin Rev Allergy       Date:  1990 Summer-Fall

Review 3.  [Causes and therapy of organ failure: mediators, their role and therapeutic implications as exemplified by the infected patient].

Authors:  H Neuhof
Journal:  Langenbecks Arch Chir       Date:  1987

4.  Proteolysis by neutrophils. Relative importance of cell-substrate contact and oxidative inactivation of proteinase inhibitors in vitro.

Authors:  E J Campbell; R M Senior; J A McDonald; D L Cox
Journal:  J Clin Invest       Date:  1982-10       Impact factor: 14.808

5.  Neutrophils degrade subendothelial matrices in the presence of alpha-1-proteinase inhibitor. Cooperative use of lysosomal proteinases and oxygen metabolites.

Authors:  S J Weiss; S Regiani
Journal:  J Clin Invest       Date:  1984-05       Impact factor: 14.808

6.  Lung injury induced by leukocytic proteases.

Authors:  A Janoff; R White; H Carp; S Harel; R Dearing; D Lee
Journal:  Am J Pathol       Date:  1979-10       Impact factor: 4.307

7.  A model of decreased functional alpha-1-proteinase inhibitor. Pulmonary pathology of dogs exposed to chloramine T.

Authors:  W R Abrams; A B Cohen; V V Damiano; A Eliraz; P Kimbel; D R Meranze; G Weinbaum
Journal:  J Clin Invest       Date:  1981-11       Impact factor: 14.808

8.  Potential mediator of inflammation. Phagocyte-derived oxidants suppress the elastase-inhibitory capacity of alpha 1-proteinase inhibitor in vitro.

Authors:  H Carp; A Janoff
Journal:  J Clin Invest       Date:  1980-11       Impact factor: 14.808

9.  Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema.

Authors:  J E Gadek; G A Fells; R L Zimmerman; S I Rennard; R G Crystal
Journal:  J Clin Invest       Date:  1981-10       Impact factor: 14.808

10.  Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages.

Authors:  R C Hubbard; G Fells; J Gadek; S Pacholok; J Humes; R G Crystal
Journal:  J Clin Invest       Date:  1991-09       Impact factor: 14.808

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