Literature DB >> 11016123

Learning and forgetting in schizophrenia.

J M Gold1, G Rehkemper, S W Binks, C J Carpenter, K Fleming, T E Goldberg, D R Weinberger.   

Abstract

Recent studies of patients with schizophrenia have consistently demonstrated marked deficits on measures of initial learning. However, contradictory results have been reported concerning retention and forgetting. The present study examined the level of initial and delayed recall of stories and visual figures in a group of 76 patients with schizophrenia and 51 normal controls. Schizophrenia patients demonstrated marked impairments in initial and delayed recall as well as significantly worse percentage retention scores. However, schizophrenia patients and healthy controls individually matched on level of initial recall had nearly identical delayed recall performance. The results suggest a primary deficit in the initial acquisition of information rather than an accelerated rate of forgetting in schizophrenia.

Entities:  

Mesh:

Year:  2000        PMID: 11016123

Source DB:  PubMed          Journal:  J Abnorm Psychol        ISSN: 0021-843X


  13 in total

Review 1.  Circumstances under which practice does not make perfect: a review of the practice effect literature in schizophrenia and its relevance to clinical treatment studies.

Authors:  Terry E Goldberg; Richard S E Keefe; Robert S Goldman; Delbert G Robinson; Philip D Harvey
Journal:  Neuropsychopharmacology       Date:  2010-01-20       Impact factor: 7.853

2.  Longitudinal alterations of executive function in non-psychotic adolescents at familial risk for schizophrenia.

Authors:  Tejas S Bhojraj; Vaibhav A Diwadkar; John A Sweeney; Konasale M Prasad; Shaun M Eack; Debra M Montrose; Matcheri S Keshavan
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2010-01-29       Impact factor: 5.067

3.  Reduction in perseverative errors with adjunctive ethyl-eicosapentaenoic acid in patients with schizophrenia: Preliminary study.

Authors:  R Reddy; S Fleet-Michaliszyn; R Condray; J K Yao; M S Keshavan; R Reddy
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2011-01-05       Impact factor: 4.006

4.  Altered myelination of the hippocampal formation in subjects with schizophrenia and bipolar disorder.

Authors:  Jessie S Chambers; Nora I Perrone-Bizzozero
Journal:  Neurochem Res       Date:  2004-12       Impact factor: 3.996

5.  Influence of kynurenine 3-monooxygenase (KMO) gene polymorphism on cognitive function in schizophrenia.

Authors:  Ikwunga Wonodi; Robert P McMahon; Nithin Krishna; Braxton D Mitchell; Judy Liu; Matthew Glassman; L Elliot Hong; James M Gold
Journal:  Schizophr Res       Date:  2014-11-14       Impact factor: 4.939

6.  Reduced context effects on retrieval in first-episode schizophrenia.

Authors:  Lucia M Talamini; Lieuwe de Haan; Dorien H Nieman; Don H Linszen; Martijn Meeter
Journal:  PLoS One       Date:  2010-04-27       Impact factor: 3.240

Review 7.  Verbal declarative memory dysfunction in schizophrenia: from clinical assessment to genetics and brain mechanisms.

Authors:  Michael A Cirillo; Larry J Seidman
Journal:  Neuropsychol Rev       Date:  2003-06       Impact factor: 7.444

8.  Nonverbal delayed recognition in the relatives of schizophrenia patients with or without schizophrenia spectrum.

Authors:  Olalla Robles; Teresa Blaxton; Helene Adami; Celso Arango; Gunvant Thaker; James Gold
Journal:  Biol Psychiatry       Date:  2007-10-03       Impact factor: 13.382

9.  Development and Pilot Testing of a Novel Compensatory Cognitive Training Intervention for People with Psychosis.

Authors:  Elizabeth W Twamley; Gauri N Savla; Cynthia H Zurhellen; Robert K Heaton; Dilip V Jeste
Journal:  Am J Psychiatr Rehabil       Date:  2008-04

10.  Dominance of objects over context in a mediotemporal lobe model of schizophrenia.

Authors:  Lucia M Talamini; Martijn Meeter
Journal:  PLoS One       Date:  2009-08-04       Impact factor: 3.240

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