G Plourde1. 1. Obesity Research Centre, Columbia University, New York, NY, USA. dr_plourde@hotmail.com
Abstract
OBJECTIVE: To review therapies for treating obese patients. QUALITY OF EVIDENCE: Advice in this paper is based mainly on the results of randomized controlled trials. Some data from smaller, more physiologic studies are included. When appropriate, advice is based on consensus. MAIN MESSAGE: Recent medical evidence indicates that a modest weight loss (5% to 10%) can alleviate symptoms of obesity-related comorbidity. Treatment of obesity should be comprehensive and integrated into a multi-component approach and should involve both patients and their families. The main challenge of obesity is maintaining a reduced weight. CONCLUSION: A multi-component approach to treating obesity can help make treatment less frustrating and more rewarding for patients and physicians.
OBJECTIVE: To review therapies for treating obesepatients. QUALITY OF EVIDENCE: Advice in this paper is based mainly on the results of randomized controlled trials. Some data from smaller, more physiologic studies are included. When appropriate, advice is based on consensus. MAIN MESSAGE: Recent medical evidence indicates that a modest weight loss (5% to 10%) can alleviate symptoms of obesity-related comorbidity. Treatment of obesity should be comprehensive and integrated into a multi-component approach and should involve both patients and their families. The main challenge of obesity is maintaining a reduced weight. CONCLUSION: A multi-component approach to treating obesity can help make treatment less frustrating and more rewarding for patients and physicians.
Authors: S W Lichtman; K Pisarska; E R Berman; M Pestone; H Dowling; E Offenbacher; H Weisel; S Heshka; D E Matthews; S B Heymsfield Journal: N Engl J Med Date: 1992-12-31 Impact factor: 91.245