Effect of 2-years' use of chlorhexidine-containing dentifrices on plaque, gingivitis, and caries.

Chlorhexidine digluconate in 0.1% and 0.4% concentrations was added to dentifrices to evaluate its effect on plaque formation, gingival conditions and caries in 73 dental students over a 2-year period. No differences were found in the Pl I and the G I indices between the active and the placebo dentifrices, but a possible effect on caries was demonstrated. Discolorations of anterior teeth and fillings were the only side effects observed.