| Literature DB >> 11012036 |
V Bénéteau1, A Pierré, B Pfeiffer, P Renard, T Besson.
Abstract
Coupling of five amines on the 7-methoxy-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline core was achieved and afforded, in particular, an opened analogue of the natural alkaloid wakayin. Evaluation of cytotoxic activity of compounds 2, 10-13 on L1210 cells afforded IC50 in the range 0.25 5.3 microM.Entities:
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Year: 2000 PMID： 11012036 DOI： 10.1016/s0960-894x(00)00450-9
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823