Literature DB >> 11011996

Hydrogen bonding in salicylsalicylic acid (salsalate) crystals.

P J Cox1, G I Gilmour, S M MacManus.   

Abstract

An X-ray crystallographic study of the drug salsalicylic acid (salsalate) has been performed. Crystal formation of the drug is influenced by both inter- and intra-molecular hydrogen bonding. In addition an OH group in salsalate can occupy alternate ortho positions resulting in two hydrogen bonding motifs within a single crystal.

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Year:  2000        PMID: 11011996     DOI: 10.1016/s0378-5173(00)00495-6

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  1 in total

1.  2-[(2-Acet-oxy-benzo-yl)-oxy]benzoic acid.

Authors:  Katarzyna A Solanko; Andrew D Bond
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-06-16
  1 in total

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