| Literature DB >> 11009379 |
Abstract
A diastereocontrolled synthesis of (+)-febrifugine, a potent antimalarial piperidine alkaloid, has been achieved using a chiral block having a bicyclo[3.2.1]octane framework which exhibits inherent convex-face selectivity.Entities:
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Year: 2000 PMID： 11009379 DOI： 10.1021/ol006384f
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005