Literature DB >> 11008496

[Epidemiology and physiopathology of chronic venous leg diseases].

P H Carpentier1.   

Abstract

Chronic venous disorders of the lower limbs include a wide range of clinical manifestations involving more than one half of the population in the industrial countries. Varicose veins have a multifactorial origin, linked to ageing, environment (life habits, pregnancies...) and heredity. Their development is related to an increased distensibility of the venous wall and to haemodynamic dysfunction secondary to valvular incompetence. Cutaneous trophic changes and leg ulcers are the final result of severe primary varicose disease or post-thrombotic disease. Elder people are mostly concerned. Skin disease results from ambulatory venous hyperpressure due to several types of reflux involving superficial, deep and perforator veins. Its development is linked to a cutaneous microangiopathy, the central element of which is a decreased capillary density. Venous symptoms are quite widespread and women are more concerned than men; they are also of a multifactorial origin, varicose veins being only one of the causative factors. Their pathogenesis remains unclear, involving venous stasis and probably a functional insufficiency of the lymphatic system.

Entities:  

Mesh:

Year:  2000        PMID: 11008496

Source DB:  PubMed          Journal:  Rev Prat        ISSN: 0035-2640


  5 in total

Review 1.  Phlebotonics for venous insufficiency.

Authors:  Maria José Martinez-Zapata; Robin W M Vernooij; Sonia Maria Uriona Tuma; Airton T Stein; Rosa M Moreno; Emilio Vargas; Dolors Capellà; Xavier Bonfill Cosp
Journal:  Cochrane Database Syst Rev       Date:  2016-04-06

Review 2.  Global impact and contributing factors in varicose vein disease development.

Authors:  Muhammad Rahil Aslam; Hafiz Muhammad Asif; Khalil Ahmad; Sana Jabbar; Abdul Hayee; Muhammad Shahid Sagheer; Jalil Ur Rehman; Sana Khalid; Abdul Sattar Hashmi; Sehrish Rana Rajpoot; Aamir Sharif
Journal:  SAGE Open Med       Date:  2022-08-25

Review 3.  Safety of calcium dobesilate in chronic venous disease, diabetic retinopathy and haemorrhoids.

Authors:  Hervé Allain; Albert A Ramelet; Elisabeth Polard; Danièle Bentué-Ferrer
Journal:  Drug Saf       Date:  2004       Impact factor: 5.228

4.  Phlebotonics for venous insufficiency.

Authors:  Maria José Martinez-Zapata; Robin Wm Vernooij; Daniel Simancas-Racines; Sonia Maria Uriona Tuma; Airton T Stein; Rosa Maria M Moreno Carriles; Emilio Vargas; Xavier Bonfill Cosp
Journal:  Cochrane Database Syst Rev       Date:  2020-11-03

5.  A multicenter review of epidemiology and management of varicose veins for national guidance.

Authors:  Nitin Joseph; Abhishai B; Mohamed Faizan Thouseef; Uma Devi M; Ayesha Abna; Isha Juneja
Journal:  Ann Med Surg (Lond)       Date:  2016-04-30
  5 in total

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