Literature DB >> 11008115

Interleukin-18 (IL-18) and infectious diseases, with special emphasis on diseases induced by intracellular pathogens.

I Sugawara1.   

Abstract

Interleukin-18 (IL-18) is a novel cytokine mainly produced by activated macrophages. IL-18 was originally called interferon-gamma inducing factor, due to its action in inducing IFN-gamma secretion from Th1 cells, NK cells and NKT cells. It has been reported that IL-18 may play important roles in various diseases including cancer and infectious diseases. This review deals with the roles of IL-18 in infectious diseases, with special emphasis on IL-18 in infectious diseases caused by intracellular pathogens including Mycobacterium tuberculosis, Mycobacterium leprae, Listeria monocytogenes and Salmonella typhimurium.

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Year:  2000        PMID： 11008115     DOI： 10.1016/s1286-4579(00)01279-x

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  15 in total

1.  Interleukin-18 promoter polymorphisms and plasma levels are associated with increased risk of periodontitis: a meta-analysis.

Authors:  Zhi-Gang Li; Jin-Juan Li; Chang-An Sun; Yuan Jin; Wei-Wei Wu
Journal:  Inflamm Res       Date:  2013-10-16       Impact factor: 4.575

2.  A defective Th1 response of the spleen in the initial phase may explain why splenectomy helps prevent a Listeria infection.

Authors:  N Kuranaga; M Kinoshita; T Kawabata; N Shinomiya; S Seki
Journal:  Clin Exp Immunol       Date:  2005-04       Impact factor: 4.330

3.  Elevated levels of circulating interleukin-18 in human immunodeficiency virus-infected individuals: role of peripheral blood mononuclear cells and implications for AIDS pathogenesis.

Authors:  Rasheed Ahmad; Sardar T A Sindhu; Emil Toma; Richard Morisset; Ali Ahmad
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

4.  Interleukin-18 and gamma interferon production by oral epithelial cells in response to exposure to Candida albicans or lipopolysaccharide stimulation.

Authors:  Mahmoud Rouabhia; Geneviève Ross; Nathalie Pagé; Jamila Chakir
Journal:  Infect Immun       Date:  2002-12       Impact factor: 3.441

5.  Cytokines involved in interferon-gamma production by human macrophages.

Authors:  Cory M Robinson; Dawn O'Dee; Travis Hamilton; Gerard J Nau
Journal:  J Innate Immun       Date:  2009-10-10       Impact factor: 7.349

6.  Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence.

Authors:  Joseph B McPhee; Patricio Mena; James B Bliska
Journal:  Infect Immun       Date:  2010-06-01       Impact factor: 3.441

7.  Recombinant Mycobacterium bovis bacillus Calmette-Guérin (BCG) expressing mouse IL-18 augments Th1 immunity and macrophage cytotoxicity.

Authors:  Y Luo; H Yamada; X Chen; A A Ryan; D P Evanoff; J A Triccas; M A O'Donnell
Journal:  Clin Exp Immunol       Date:  2004-07       Impact factor: 4.330

8.  Interleukin-18-related genes are induced during the contraction phase but do not play major roles in regulating the dynamics or function of the T-cell response to Listeria monocytogenes infection.

Authors:  Jodie S Haring; John T Harty
Journal:  Infect Immun       Date:  2009-02-17       Impact factor: 3.441

9.  CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection.

Authors:  Richardson Fleuridor; Brian Wilson; Runhua Hou; Alan Landay; Harold Kessler; Lena Al-Harthi
Journal:  Immunology       Date:  2003-01       Impact factor: 7.397

10.  Immunological surrogate marker of rAls3p-N vaccine-induced protection against Staphylococcus aureus.

Authors:  Lin Lin; Ashraf S Ibrahim; Beverlie Baquir; Valentina Avanesian; Yue Fu; Brad Spellberg
Journal:  FEMS Immunol Med Microbiol       Date:  2009-01-13
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