Literature DB >> 11007978

Cleavage of yeast tRNAPhe with complementary oligonucleotide conjugated to a small ribonuclease mimic.

N G Beloglazova1, V N Sil'nikov, M A Zenkova, V V Vlassov.   

Abstract

An oligonucleotide conjugate bearing a chemical construct mimicking the catalytic center of ribonuclease A has been designed and studied. The conjugate efficiently cleaves yeast tRNAPhe at a single site adjacent to the target complementary sequence.

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Year:  2000        PMID： 11007978     DOI： 10.1016/s0014-5793(00)02029-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

1.  Sequence-specific artificial ribonucleases. I. Bis-imidazole-containing oligonucleotide conjugates prepared using precursor-based strategy.

Authors:  Natalia G Beloglazova; Martin M Fabani; Marina A Zenkova; Elena V Bichenkova; Nikolai N Polushin; Vladimir V Sil'nikov; Kenneth T Douglas; Valentin V Vlassov
Journal:  Nucleic Acids Res       Date:  2004-07-23       Impact factor: 16.971

2.  Hydrolysis of bulged nucleotides in hybrids formed by RNA and imidazole-derivatized oligo-2'-O-methylribonucleotides.

Authors:  Anthony D Saleh; Paul S Miller
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2011-03       Impact factor: 1.381

3.  Polyamine derivatives as selective RNaseA mimics.

Authors:  Sandra Fouace; Cyril Gaudin; Sylvie Picard; Sophie Corvaisier; Jacques Renault; Bertrand Carboni; Brice Felden
Journal:  Nucleic Acids Res       Date:  2004-01-02       Impact factor: 16.971

4.  Site-selective artificial ribonucleases: oligonucleotide conjugates containing multiple imidazole residues in the catalytic domain.

Authors:  Natalia G Beloglazova; Martin M Fabani; Nikolai N Polushin; Vladimir V Sil'nikov; Valentin V Vlassov; Elena V Bichenkova; Marina A Zenkova
Journal:  J Nucleic Acids       Date:  2011-09-25
  4 in total

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