| Literature DB >> 11006542 |
T C Bruice1, K Kahn.
Abstract
Recent advances in computational methods and the availability of fast, affordable computers have made the modeling of enzymatic reactions practical. The remaining challenges include achieving the accuracy level at which thermodynamic parameters and kinetic constants for different substrates, mutant enzymes, or in the presence of allosteric effectors can be predicted quantitatively.Mesh：
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Year: 2000 PMID： 11006542 DOI： 10.1016/s1367-5931(00)00129-0
Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822