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Literature DB >> 1100607

Transfer ribonucleic acid methylase deficiency found in UGA supressor strains.

Abstract

Extracts of recessive UGA suppressor strains, designated supK, are deficient in transfer ribonucleic acid (tRNA)-methylating activity when compared to wild-type extracts. Moreover, the tRNA from suppressor strains is methyl deficient when compared to wild-type tRNA. This deficiency is due to the lack of a single tRNA methylase activity in suppressor strains. UGA suppressor activity may be caused by the miscoding of one or more methyl-deficient tRNA's in supK strains.

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Year: 1975 PMID： 1100607 PMCID： PMC235900 DOI： 10.1128/jb.124.1.332-340.1975

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

32 in total

1. AMINO ACID ACCEPTOR ACTIVITY OF ENZYMICALLY ALTERED SOLUBLE RNA FROM ESCHERICHIA COLI.

Authors: S NISHIMURA; G D NOVELLI
Journal: Biochim Biophys Acta Date: 1964-04-27

2. THE ENZYMATIC METHYLATION OF RIBONUCLEIC ACID AND DEOXYRIBONUCLEIC ACID. 3. PURIFICATION OF SOLUBLE RIBONUCLEIC ACID-METHYLATING ENZYMES.

Authors: J HURWITZ; M GOLD; M ANDERS
Journal: J Biol Chem Date: 1964-10 Impact factor: 5.157

3. STUDIES ON POLYNUCLEOTIDES. XLI. PURIFICATION OF PHENYLALANINE-SPECIFIC TRANSFER RIBONUCLEIC ACID FROM YEAST BY COUNTERCURRENT DISTRIBUTION.

Authors: R M HOSKINSON; H G KHORANA
Journal: J Biol Chem Date: 1965-05 Impact factor: 5.157

4. THE SPECIES VARIATION OF RNA METHYLASE.

Authors: P R Srinivasan; E Borek
Journal: Proc Natl Acad Sci U S A Date: 1963-04 Impact factor: 11.205

5. A single mutational modification of a tryptophan-specific transfer RNA permits aminoacylation by glutamine and translation of the codon UAG.

Authors: M Yaniv; W R Folk; P Berg; L Soll
Journal: J Mol Biol Date: 1974-06-25 Impact factor: 5.469

6. Mutational alterations of tryptophan-specific transfer RNA that generate translation suppressors of the UAA, UAG and UGA nonsense codons.

Authors: L Soll
Journal: J Mol Biol Date: 1974-06-25 Impact factor: 5.469

7. UGA and non-triplet suppressor reading of the genetic code.

Authors: J F Atkins; S Ryce
Journal: Nature Date: 1974-06-07 Impact factor: 49.962

8. [Mutant tRNA His ineffective in repression and lacking two pseudouridine modifications].

Authors: C E Singer; G R Smith; R Cortese; B N Ames
Journal: Nat New Biol Date: 1972-07-19

9. A recessive UGA suppressor.

Authors: R H Reeves; J R Roth
Journal: J Mol Biol Date: 1971-03-28 Impact factor: 5.469

10. S-Adenosylmethionine synthetase deficient mutants of Escherichia coli K-12 with impaired control of methionine biosynthesis.

Authors: R C Greene; C H Su; C T Holloway
Journal: Biochem Biophys Res Commun Date: 1970-03-27 Impact factor: 3.575

19 in total

1. Autogenous suppression of an opal mutation in the gene encoding peptide chain release factor 2.

Authors: K Kawakami; Y Nakamura
Journal: Proc Natl Acad Sci U S A Date: 1990-11 Impact factor: 11.205

Review 2. A gripping tale of ribosomal frameshifting: extragenic suppressors of frameshift mutations spotlight P-site realignment.

Authors: John F Atkins; Glenn R Björk
Journal: Microbiol Mol Biol Rev Date: 2009-03 Impact factor: 11.056

6. General screening procedure for RNA modificationless mutants: isolation of Escherichia coli strains with specific defects in RNA methylation.

Authors: G R Björk; K Kjellin-Stråby
Journal: J Bacteriol Date: 1978-02 Impact factor: 3.490

7. The identification of the tRNA substrates for the supK tRNA methylase.

Authors: W T Pope; A Brown; R H Reeves
Journal: Nucleic Acids Res Date: 1978-03 Impact factor: 16.971

8. Escherichia coli mutants with defects in the biosynthesis of 5-methylaminomethyl-2-thio-uridine or 1-methylguanosine in their tRNA.