Literature DB >> 1100401

An inhibitory effect of thymidine on its own conversion to nucleotide in Escherichia coli.

R Hosono, S Kuno.   

Abstract

The cellular levels of thymidine nucleotide pool in thymine-requiring mutants of Escherichia coli were followed. The pool levels of dTDP, dTTP and compound-X reached maximal values in much lower concentration of thymidine than those in thymine. In higher concentrations of thymidine, an inhibitory effect on its own conversion to nucleotide was observed. The inhibited step was suggested to be the conversion of dTMP to dTDP.

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Year:  1975        PMID: 1100401     DOI: 10.1111/j.1432-1033.1975.tb02288.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  3 in total

1.  Effect of thymine concentration on cell shape in Thy- Escherichia coli B/r.

Authors:  P A Meacock; R H Pritchard; E M Roberts
Journal:  J Bacteriol       Date:  1978-01       Impact factor: 3.490

2.  Thymidine sensitivity of certain strains of Escherichia coli K12.

Authors:  S I Ahmad; A Eisenstark
Journal:  Mol Gen Genet       Date:  1979-05-04

3.  Interaction of an Escherichia coli mutator gene with a deoxyribonucleotide effector.

Authors:  H A Erlich; E C Cox
Journal:  Mol Gen Genet       Date:  1980
  3 in total

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