Literature DB >> 1100397

Isolation and properties of a thymidylate-less mutant in Saccharomyces cerevisiae.

M Luzzati.   

Abstract

A mutant, tmp3, has been isolated in Saccharomyces cerevisiae. Genetic and physiological analysis show that a single mendelian gene controls the multiple requirements for thymidylate, methionine, adenine and histidine and a neutral cytoplasmic petite character. Crude extracts of this mutant present a 60% decrease of serine transhydroxymethylase specific activity as compared to a wild-type strain.

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Year:  1975        PMID： 1100397     DOI： 10.1111/j.1432-1033.1975.tb02259.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN： 0014-2956


  8 in total

1.  Molecular characterization of the Saccharomyces cerevisiae dihydrofolate reductase gene (DFR1).

Authors:  P A Lagosky; G R Taylor; R H Haynes
Journal:  Nucleic Acids Res       Date:  1987-12-23       Impact factor: 16.971

2.  Yeast cell-cycle mutant cdc21 is a temperature-sensitive thymidylate auxotroph.

Authors:  J C Game
Journal:  Mol Gen Genet       Date:  1976-08-02

3.  Influence of the nuclear gene tmp3 on the loss of mitochondrial genes in Saccharomyces cerevisiae.

Authors:  R Zelikson; M Luzzati
Journal:  Mol Cell Biol       Date:  1982-04       Impact factor: 4.272

4.  Absence of MMF1 disrupts heme biosynthesis by targeting Hem1pin Saccharomyces cerevisiae.

Authors:  Gregory H Whitaker; Dustin C Ernst; Diana M Downs
Journal:  Yeast       Date:  2021-10-10       Impact factor: 3.325

5.  Construction of a new vector conferring methotrexate resistance in Nicotiana tabacum plants.

Authors:  T Irdani; P Bogani; A Mengoni; G Mastromei; M Buiatti
Journal:  Plant Mol Biol       Date:  1998-08       Impact factor: 4.076

6.  Isolation and characterization of yeast mutants auxotrophic for 2'-deoxythymidine 5'-monophosphate.

Authors:  J G Little; R H Haynes
Journal:  Mol Gen Genet       Date:  1979-01-10

7.  Growth inhibition of Candida albicans by folate pathway inhibitors. Their potential in the selection of auxotrophs.

Authors:  O E Henson; D O McClary
Journal:  Antonie Van Leeuwenhoek       Date:  1979       Impact factor: 2.271

8.  Mmf1p Couples Amino Acid Metabolism to Mitochondrial DNA Maintenance in Saccharomyces cerevisiae.

Authors:  Dustin C Ernst; Diana M Downs
Journal:  mBio       Date:  2018-02-27       Impact factor: 7.867
  8 in total

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