| Literature DB >> 11002326 |
Abstract
Ischemia/reperfusion injury is often the final and irreversible factor causing flap failure in microvascular surgery for head and neck defects. This paper begins with a detailed review of flap physiology and ischemia/reperfusion injury at the cellular level. Subsequently, the pharmacotherapeutic agents used clinically and experimentally to avoid or reverse ischemia/reperfusion injury are discussed. The goal of this review is to provide a framework for understanding the expanding body of literature relevant to ischemia/reperfusion injury in microvascular surgery. Copyright 2000 John Wiley & Sons, Inc.Entities:
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Year: 2000 PMID: 11002326 DOI: 10.1002/1097-0347(200010)22:7<700::aid-hed10>3.0.co;2-h
Source DB: PubMed Journal: Head Neck ISSN: 1043-3074 Impact factor: 3.147