Literature DB >> 11000036

Two novel cytotoxic benzofuran derivatives from Brazilian propolis.

A H Banskota1, Y Tezuka, K Midorikawa, K Matsushige, S Kadota.   

Abstract

Two novel benzofuran derivatives, propolis-benzofurans A (1) and B (2), were isolated from the MeOH extract of Brazilian propolis, together with two known isoprenylated compounds (E)-3-[2, 3-dihydro-2-(1-methylethenyl)-7-prenyl-5-benzofuranyl]-2-propen oic acid and (E)-3-¿4-hydroxy-3-[(E)-4-(2, 3-dihydrocinnamoyloxy)-3-methyl-2-butenyl]-5-prenylphenyl¿-2 -propenoi c acid. The structures of these compounds were elucidated on the basis of spectral analysis. Both the new compounds exhibited mild cytotoxicity toward highly liver-metastatic murine colon 26-L5 carcinoma and human HT-1080 fibrosarcoma cells.

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Year:  2000        PMID: 11000036     DOI: 10.1021/np000143z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  11 in total

1.  Creating molecular diversity from antioxidants in Brazilian propolis. Combination of TOPS-MODE QSAR and virtual structure generation.

Authors:  Ernesto Estrada; Jose A Quincoces; Grace Patlewicz
Journal:  Mol Divers       Date:  2004       Impact factor: 2.943

2.  Synthesis of 2,3-disubstituted benzo[b]furans by the palladium-catalyzed coupling of o-iodoanisoles and terminal alkynes, followed by electrophilic cyclization.

Authors:  Dawei Yue; Tuanli Yao; Richard C Larock
Journal:  J Org Chem       Date:  2005-12-09       Impact factor: 4.354

3.  Total Synthesis of Propolisbenzofuran B.

Authors:  Brian T Jones; Christopher T Avetta; Regan J Thomson
Journal:  Chem Sci       Date:  2014-05-01       Impact factor: 9.825

4.  Studies toward the synthesis of the epoxykinamycin FL-120B': discovery of a decarbonylative photocyclization.

Authors:  Stephen S Scully; John A Porco
Journal:  Org Lett       Date:  2012-05-09       Impact factor: 6.005

5.  A novel and facile synthesis of 3-(2-benzofuroyl)- and 3,6-bis(2-benzofuroyl)carbazole derivatives.

Authors:  Wentao Gao; Meiru Zheng; Yang Li
Journal:  Beilstein J Org Chem       Date:  2011-11-17       Impact factor: 2.883

6.  Bioactive constituents of brazilian red propolis.

Authors:  Boryana Trusheva; Milena Popova; Vassya Bankova; Svetlana Simova; Maria Cristina Marcucci; Patricia Laguna Miorin; Flavia da Rocha Pasin; Iva Tsvetkova
Journal:  Evid Based Complement Alternat Med       Date:  2006-05-03       Impact factor: 2.629

7.  Origin and Chemical Variation of Brazilian Propolis.

Authors:  Antonio Salatino; Erica Weinstein Teixeira; Giuseppina Negri; Dejair Message
Journal:  Evid Based Complement Alternat Med       Date:  2005-02-09       Impact factor: 2.629

8.  Identification and Determination of Seven Phenolic Acids in Brazilian Green Propolis by UPLC-ESI-QTOF-MS and HPLC.

Authors:  Shengwei Sun; Meijuan Liu; Jian He; Kunping Li; Xuguang Zhang; Guangling Yin
Journal:  Molecules       Date:  2019-05-09       Impact factor: 4.411

9.  Induction of apoptosis by a potent caffeic acid derivative, caffeic acid undecyl ester, is mediated by mitochondrial damage in NALM-6 human B cell leukemia cells.

Authors:  Ayako Tomizawa; Syu-ichi Kanno; Yuu Osanai; Akane Goto; Chizuru Sato; Shin Yomogida; Masaaki Ishikawa
Journal:  Oncol Rep       Date:  2012-12-03       Impact factor: 3.906

10.  A detailed computational investigation on the structural and spectroscopic properties of propolisbenzofuran B.

Authors:  Morteza Rouhani
Journal:  Heliyon       Date:  2019-10-08
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