| Literature DB >> 10999438 |
H Goto1, I Sakakibara, Y Shimada, Y Kasahara, K Terasawa.
Abstract
Uncariae ramulus et Uncus (URE) has a vasodilator effect. Its mechanism consists of not only endothelium-independent relaxation with Ca2+ channel blocking effect but also endothelium-dependent relaxation with nitric oxide. The active components are alkaloids and tannin contained in Uncariae ramulus et Uncus. They also show a superoxide dismutase-like effect and suppressed vasocontraction induced by xanthine and xanthine oxidase. These mechanisms may also influence vasodilatation by Uncariae ramulus et Uncus in vivo.Entities:
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Year: 2000 PMID： 10999438 DOI： 10.1142/S0192415X00000246
Source DB: PubMed Journal: Am J Chin Med ISSN： 0192-415X Impact factor: 4.667