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Literature DB >> 10998752

Interleukin 18 (IL-18) levels in patients with sepsis.

S Endo¹, K Inada, Y Yamada, G Wakabayashi, H Ishikura, T Tanaka, S Sato.

Abstract

IL-18 levels in the blood of 13 sepsis patients were assessed. The IL-18 values were significantly correlated with their Acute Physiology and Chronic Health Evaluation (APACHE) II scores, and they were a good reflection of the severity of the disease. There was also a strong correlation between the IL-18 values and the patients' inflammatory cytokine levels. The results suggested strong involvement of IL-18 in the pathogenesis of sepsis.

Entities: Disease Gene Species

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Year: 2000 PMID： 10998752

Source DB: PubMed Journal: J Med ISSN： 0025-7850

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Cited

8 in total

1. Interleukin-18 levels reflect the long-term prognosis of acute lung injury and acute respiratory distress syndrome.

Authors: Hideyuki Makabe; Masahiro Kojika; Gaku Takahashi; Naoya Matsumoto; Shigehiro Shibata; Yasushi Suzuki; Yoshihiro Inoue; Shigeatsu Endo
Journal: J Anesth Date: 2012-05-26 Impact factor: 2.078

2. Endogenous interleukin 18 suppresses hyperglycemia and hyperinsulinemia during the acute phase of endotoxemia in mice.

Authors: Hayato Yamashita; Michiko Aoyama-Ishikawa; Miki Takahara; Chisato Yamauchi; Taketo Inoue; Makoto Miyoshi; Noriaki Maeshige; Makoto Usami; Atsunori Nakao; Joji Kotani
Journal: Surg Infect (Larchmt) Date: 2015-02-04 Impact factor: 2.150

3. Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis.

Authors: W Joost Wiersinga; Catharina W Wieland; Gerritje J W van der Windt; Anita de Boer; Sandrine Florquin; Arjen Dondorp; Nicholas P Day; Sharon J Peacock; Tom van der Poll
Journal: Infect Immun Date: 2007-05-21 Impact factor: 3.441

Review 4. Circular RNAs in Sepsis: Biogenesis, Function, and Clinical Significance.

Authors: Jesús Beltrán-García; Rebeca Osca-Verdegal; Elena Nacher-Sendra; Federico V Pallardó; José Luis García-Giménez
Journal: Cells Date: 2020-06-25 Impact factor: 6.600

5. Increased expression of Toll-like receptors 2, 3, 4 and 7 mRNA in the kidney and intestine of a septic mouse model.

Authors: Sylvia Krivan; Alkistis Kapelouzou; Stylianos Vagios; Diamantis I Tsilimigras; Michalis Katsimpoulas; Demetrios Moris; Chrysostomos V Aravanis; Theano D Demesticha; Dimitrios Schizas; Manolis Mavroidis; Kitty Pavlakis; Anastasios Machairas; Evangelos Misiakos; Theodore Liakakos
Journal: Sci Rep Date: 2019-03-08 Impact factor: 4.379

Interleukin 18 (IL-18) levels in patients with sepsis.

1. Interleukin-18 levels reflect the long-term prognosis of acute lung injury and acute respiratory distress syndrome.

2. Endogenous interleukin 18 suppresses hyperglycemia and hyperinsulinemia during the acute phase of endotoxemia in mice.

3. Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis.

Review 4. Circular RNAs in Sepsis: Biogenesis, Function, and Clinical Significance.

5. Increased expression of Toll-like receptors 2, 3, 4 and 7 mRNA in the kidney and intestine of a septic mouse model.

6. Circulating LIGHT (TNFSF14) and Interleukin-18 Levels in Sepsis-Induced Multi-Organ Injuries.

7. Elevations of novel cytokines in bacterial meningitis in infants.

Review 8. Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids.