Literature DB >> 10997605

Relationship between regional fat distribution and insulin resistance.

E Bonora1.   

Abstract

Visceral fat is a strong predictor of insulin resistance in obese subjects, but not in normal weight individuals, suggesting that this association might occur only beyond a certain threshold of visceral fat amount. Unlike subcutaneous fat, increased visceral fat is associated with increased hepatic glucose production and reduced glucose disposal. This association is independent of the methodology used to assess insulin sensitivity in humans. This article reviews all relevant data coming from epidemiological, clinical and interventional (weight loss) studies and studies obtained in identical twins.

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Year:  2000        PMID: 10997605     DOI: 10.1038/sj.ijo.0801274

Source DB:  PubMed          Journal:  Int J Obes Relat Metab Disord


  18 in total

Review 1.  Increased risk of cardiovascular disease and chronic kidney disease in NAFLD.

Authors:  Enzo Bonora; Giovanni Targher
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2012-05-08       Impact factor: 46.802

2.  Metabolic subtypes and risk of mortality in normal weight, overweight, and obese individuals with CKD.

Authors:  Lynae J Hanks; Rikki M Tanner; Paul Muntner; Holly Kramer; William M McClellan; David G Warnock; Suzanne E Judd; Orlando M Gutiérrez
Journal:  Clin J Am Soc Nephrol       Date:  2013-10-31       Impact factor: 8.237

3.  Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice.

Authors:  Galyna Bryzgalova; Lovisa Lundholm; Neil Portwood; Jan-Ake Gustafsson; Akhtar Khan; Suad Efendic; Karin Dahlman-Wright
Journal:  Am J Physiol Endocrinol Metab       Date:  2008-08-12       Impact factor: 4.310

4.  Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio.

Authors:  D Schleinitz; N Klöting; C M Lindgren; J Breitfeld; A Dietrich; M R Schön; T Lohmann; M Dreßler; M Stumvoll; M I McCarthy; M Blüher; P Kovacs
Journal:  Int J Obes (Lond)       Date:  2013-04-19       Impact factor: 5.095

5.  Liver steatosis: investigation of opposed-phase T1-weighted liver MR signal intensity loss and visceral fat measurement as biomarkers.

Authors:  Manisha Bahl; Aliya Qayyum; Antonio C Westphalen; Susan M Noworolski; Philip W Chu; Linda Ferrell; Phyllis C Tien; Nathan M Bass; Raphael B Merriman
Journal:  Radiology       Date:  2008-10       Impact factor: 11.105

6.  Ethnicity and weight status affect the accuracy of proxy indices of insulin sensitivity.

Authors:  Jessica A Alvarez; Nikki C Bush; Gary R Hunter; David W Brock; Barbara A Gower
Journal:  Obesity (Silver Spring)       Date:  2008-10-16       Impact factor: 5.002

7.  Racial differences in body fat distribution among reproductive-aged women.

Authors:  Mahbubur Rahman; Jeff R Temple; Carmen Radecki Breitkopf; Abbey B Berenson
Journal:  Metabolism       Date:  2009-06-18       Impact factor: 8.694

Review 8.  What is the relationship between exercise and metabolic abnormalities? A review of the metabolic syndrome.

Authors:  Sean Carroll; Mike Dudfield
Journal:  Sports Med       Date:  2004       Impact factor: 11.136

9.  High ApoD protein level in the round ligament fat depot of severely obese women is associated with an improved inflammatory profile.

Authors:  Frederik Desmarais; Karl-F Bergeron; Michel Lacaille; Isabelle Lemieux; Jean Bergeron; Simon Biron; Eric Rassart; Denis R Joanisse; Pascale Mauriege; Catherine Mounier
Journal:  Endocrine       Date:  2018-06-04       Impact factor: 3.633

10.  Low-fat versus low-carbohydrate weight reduction diets: effects on weight loss, insulin resistance, and cardiovascular risk: a randomized control trial.

Authors:  Una Bradley; Michelle Spence; C Hamish Courtney; Michelle C McKinley; Cieran N Ennis; David R McCance; Jane McEneny; Patrick M Bell; Ian S Young; Steven J Hunter
Journal:  Diabetes       Date:  2009-08-31       Impact factor: 9.461

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