Literature DB >> 10996809

Glycoprotein degradation: do sugars hold the key?

L Frigerio1, J M Lord.   

Abstract

Secretory glycoproteins that fail to fold or assemble correctly are retained in the endoplasmic reticulum and eventually degraded. Recent evidence shows that trimming of their N-linked oligosaccharide chains plays a key role in targeting glycoproteins for destruction.

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Year:  2000        PMID： 10996809     DOI： 10.1016/s0960-9822(00)00680-1

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  7 in total

1.  Ricin A chain without its partner B chain is degraded after retrotranslocation from the endoplasmic reticulum to the cytosol in plant cells.

Authors:  A Di Cola; L Frigerio; J M Lord; A Ceriotti; L M Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-04       Impact factor: 11.205

2.  Endo-beta-N-acetylglucosaminidase, an enzyme involved in processing of free oligosaccharides in the cytosol.

Authors:  Tadashi Suzuki; Keiichi Yano; Seiji Sugimoto; Ken Kitajima; William J Lennarz; Sadako Inoue; Yasuo Inoue; Yasufumi Emori
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-11       Impact factor: 11.205

3.  Endoplasmic reticulum-associated degradation of ricin A chain has unique and plant-specific features.

Authors:  Alessandra Di Cola; Lorenzo Frigerio; J Michael Lord; Lynne M Roberts; Aldo Ceriotti
Journal:  Plant Physiol       Date:  2004-12-23       Impact factor: 8.340

4.  Folding of hepatitis C virus E1 glycoprotein in a cell-free system.

Authors:  M Merola; M Brazzoli; F Cocchiarella; J M Heile; A Helenius; A J Weiner; M Houghton; S Abrignani
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

5.  N-linked oligosaccharides play a role in disulphide-dependent dimerization of intestinal mucin Muc2.

Authors:  Sherilyn L Bell; Gongqiao Xu; Ismat A Khatri; Rongquan Wang; Sameera Rahman; Janet F Forstner
Journal:  Biochem J       Date:  2003-08-01       Impact factor: 3.857

6.  Organizational diversity among distinct glycoprotein endoplasmic reticulum-associated degradation programs.

Authors:  Christopher M Cabral; Yan Liu; Kelley W Moremen; Richard N Sifers
Journal:  Mol Biol Cell       Date:  2002-08       Impact factor: 4.138

7.  Endoplasmic Reticulum-Associated rht-PA Processing in CHO Cells: Influence of Mild Hypothermia and Specific Growth Rates in Batch and Chemostat Cultures.

Authors:  Mauricio Vergara; Julio Berrios; Irene Martínez; Alvaro Díaz-Barrera; Cristian Acevedo; Juan G Reyes; Ramon Gonzalez; Claudia Altamirano
Journal:  PLoS One       Date:  2015-12-11       Impact factor: 3.240
  7 in total

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