Literature DB >> 10996803

Actin cytoskeleton: thinking globally, actin' locally.

L M Lanier1, F B Gertler.   

Abstract

A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating actin-based cell motility and morphogenesis.

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Year:  2000        PMID: 10996803     DOI: 10.1016/s0960-9822(00)00685-0

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  5 in total

1.  Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale.

Authors:  Jacco van Rheenen; Kees Jalink
Journal:  Mol Biol Cell       Date:  2002-09       Impact factor: 4.138

2.  A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.

Authors:  Katarina Hattula; Johanna Furuhjelm; Airi Arffman; Johan Peränen
Journal:  Mol Biol Cell       Date:  2002-09       Impact factor: 4.138

3.  Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.

Authors:  Cecilia J Bonangelino; Johnathan J Nau; Jason E Duex; Mikala Brinkman; Andrew E Wurmser; Jonathan D Gary; Scott D Emr; Lois S Weisman
Journal:  J Cell Biol       Date:  2002-03-11       Impact factor: 10.539

Review 4.  Phosphoinositides Signaling and Epithelial-to-Mesenchymal Transition: Putative Topic for Basic Toxicological Research.

Authors:  Chang Ho Lee
Journal:  Toxicol Res       Date:  2008-03-01

5.  Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway.

Authors:  Brian P Ziemba; John E Burke; Glenn Masson; Roger L Williams; Joseph J Falke
Journal:  Biophys J       Date:  2016-04-26       Impact factor: 4.033

  5 in total

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