Literature DB >> 10996731

Synergistic cooperation between water-soluble chitosan oligomers and interferon-gamma for induction of nitric oxide synthesis and tumoricidal activity in murine peritoneal macrophages.

W G Seo1, H O Pae, N Y Kim, G S Oh, I S Park, Y H Kim, Y M Kim, Y H Lee, C D Jun, H T Chung.   

Abstract

The effects of water-soluble chitosan oligomers (WSCO) on the synthesis of nitric oxide (NO) by murine peritoneal macrophages and on macrophage-mediated cytotoxicity towards murine fibrosarcoma Meth A cells were investigated. WSCO alone had no effect on NO synthesis and killing of tumor cells. However, treatment of macrophages with a combination of WSCO and interferon-gamma (IFN-gamma) synergically increased NO synthesis and enhanced killing of tumor cells. The synergism between IFN-gamma and WSCO in NO synthesis and tumoricidal activity was mainly dependent on increased secretion of tumor necrosis factor-alpha by WSCO.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10996731     DOI： 10.1016/s0304-3835(00)00551-6

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  7 in total

1.  Extraction of Chitosan with Different Physicochemical Properties from Cunninghamella echinulata (Thaxter) Thaxter for Biological Applications.

Authors:  Shajahan Azeez; Anbazhagan Sathiyaseelan; Ezekiel Raj Jeyaraj; Kandasamy Saravanakumar; Myeong-Hyeon Wang; Venkatesan Kaviyarasan
Journal:  Appl Biochem Biotechnol       Date:  2022-07-20       Impact factor: 3.094

2.  Immunoadjuvant chemotherapy of visceral leishmaniasis in hamsters using amphotericin B-encapsulated nanoemulsion template-based chitosan nanocapsules.

Authors:  Shalini Asthana; Anil K Jaiswal; Pramod K Gupta; Vivek K Pawar; Anuradha Dube; Manish K Chourasia
Journal:  Antimicrob Agents Chemother       Date:  2013-01-28       Impact factor: 5.191

Review 3.  Keeping track of the growing number of biological functions of chitin and its interaction partners in biomedical research.

Authors:  Bjørn E V Koch; Jens Stougaard; Herman P Spaink
Journal:  Glycobiology       Date:  2015-01-16       Impact factor: 4.313

4.  Anti-cancer efficacy of biotinylated chitosan nanoparticles in liver cancer.

Authors:  Mingrong Cheng; Weiping Zhu; Qing Li; Dejian Dai; Yiming Hou
Journal:  Oncotarget       Date:  2017-07-10

Review 5.  Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action.

Authors:  Hari Sharan Adhikari; Paras Nath Yadav
Journal:  Int J Biomater       Date:  2018-12-30

6.  TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation.

Authors:  Ei'ichi Iizasa; Yasushi Chuma; Takayuki Uematsu; Mio Kubota; Hiroaki Kawaguchi; Masayuki Umemura; Kenji Toyonaga; Hideyasu Kiyohara; Ikuya Yano; Marco Colonna; Masahiko Sugita; Goro Matsuzaki; Sho Yamasaki; Hiroki Yoshida; Hiromitsu Hara
Journal:  Nat Commun       Date:  2021-04-16       Impact factor: 14.919

7.  Combined Effects of Sodium Substitution and Addition of Cellulose or Chitosan on Quality Properties of Pork Sausages.

Authors:  Sang Keun Jin; Sun Jin Hur; Dong Gyun Yim
Journal:  Food Sci Anim Resour       Date:  2019-08-31
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.