Literature DB >> 10996528

Adipose tissue as an endocrine organ.

R S Ahima1, J S Flier.   

Abstract

The discovery of leptin in the mid-1990s has focused attention on the role of proteins secreted by adipose tissue. Leptin has profound effects on appetite and energy balance, and is also involved in the regulation of neuroendocrine and immune function. Sex steroid and glucocorticoid metabolism in adipose tissue has been implicated as a determinant of body fat distribution and cardiovascular risk. Other adipose products, for example, proinflammatory cytokines, complement factors and components of the coagulation/fibrinolytic cascade, may mediate the metabolic and cardiovascular complications associated with obesity.

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Year:  2000        PMID： 10996528     DOI： 10.1016/s1043-2760(00)00301-5

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  285 in total

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Review 8.  Association of endocrine disruptors and obesity: perspectives from epidemiological studies.

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10.  Serum leptin levels and reproductive function during the menstrual cycle.

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