| Literature DB >> 10996086 |
A Wodarz1.
Abstract
The Drosophila tumor suppressor genes scribble, discs large and lethal giant larvae appear to act in a common pathway. Mutations in any of these genes lead to loss of apical-basal cell polarity and overproliferation of epithelia, revealing a close connection between cytoarchitecture and growth control.Entities:
Mesh:
Year: 2000 PMID: 10996086 DOI: 10.1016/s0960-9822(00)00658-8
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834