Literature DB >> 10996086

Tumor suppressors: linking cell polarity and growth control.

A Wodarz1.   

Abstract

The Drosophila tumor suppressor genes scribble, discs large and lethal giant larvae appear to act in a common pathway. Mutations in any of these genes lead to loss of apical-basal cell polarity and overproliferation of epithelia, revealing a close connection between cytoarchitecture and growth control.

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Year:  2000        PMID: 10996086     DOI: 10.1016/s0960-9822(00)00658-8

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  24 in total

1.  Brush border myosin Ia has tumor suppressor activity in the intestine.

Authors:  Rocco Mazzolini; Higinio Dopeso; Silvia Mateo-Lozano; Wakam Chang; Paulo Rodrigues; Sarah Bazzocco; Hafid Alazzouzi; Stefania Landolfi; Javier Hernández-Losa; Elena Andretta; Pia Alhopuro; Eloy Espín; Manel Armengol; Josep Tabernero; Santiago Ramón y Cajal; Matthias Kloor; Johannes Gebert; John M Mariadason; Simo Schwartz; Lauri A Aaltonen; Mark S Mooseker; Diego Arango
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-18       Impact factor: 11.205

2.  Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin.

Authors:  S T Mees; R Mennigen; T Spieker; E Rijcken; N Senninger; J Haier; M Bruewer
Journal:  Int J Colorectal Dis       Date:  2009-01-29       Impact factor: 2.571

3.  A systematic analysis of human papillomavirus (HPV) E6 PDZ substrates identifies MAGI-1 as a major target of HPV type 16 (HPV-16) and HPV-18 whose loss accompanies disruption of tight junctions.

Authors:  Christian Kranjec; Lawrence Banks
Journal:  J Virol       Date:  2010-12-01       Impact factor: 5.103

4.  Regulation of the DLG tumor suppressor by β-catenin.

Authors:  Vanitha Krishna Subbaiah; Nisha Narayan; Paola Massimi; Lawrence Banks
Journal:  Int J Cancer       Date:  2012-03-28       Impact factor: 7.396

Review 5.  Apical protein transport and lumen morphogenesis in polarized epithelial cells.

Authors:  Carly Willenborg; Rytis Prekeris
Journal:  Biosci Rep       Date:  2011-08       Impact factor: 3.840

6.  ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini.

Authors:  S K Muthuswamy; D Li; S Lelievre; M J Bissell; J S Brugge
Journal:  Nat Cell Biol       Date:  2001-09       Impact factor: 28.824

7.  The yeast tumor suppressor homologue Sro7p is required for targeting of the sodium pumping ATPase to the cell surface.

Authors:  Ingrid Wadskog; Annabelle Forsmark; Guendalina Rossi; Catherine Konopka; Mattias Oyen; Mattias Goksör; Hans Ronne; Patrick Brennwald; Lennart Adler
Journal:  Mol Biol Cell       Date:  2006-09-27       Impact factor: 4.138

8.  scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila.

Authors:  Anthony M Brumby; Helena E Richardson
Journal:  EMBO J       Date:  2003-11-03       Impact factor: 11.598

Review 9.  Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug-induced apoptosis.

Authors:  Cheng-Jeng Tai; Chung-Huei Hsu; Shing-Chuan Shen; Woan-Ruoh Lee; Ming-Chung Jiang
Journal:  J Exp Clin Cancer Res       Date:  2010-08-11

10.  Yeast lacking the SRO7/SOP1-encoded tumor suppressor homologue show increased susceptibility to apoptosis-like cell death on exposure to NaCl stress.

Authors:  Ingrid Wadskog; Corinna Maldener; Astrid Proksch; Frank Madeo; Lennart Adler
Journal:  Mol Biol Cell       Date:  2004-01-12       Impact factor: 4.138

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