Literature DB >> 10995037

Oxidative stress resistance: a robust correlated response to selection in extended longevity lines of Drosophila melanogaster?

L G Harshman1, B A Haberer.   

Abstract

Stress resistance is associated with longevity in Drosophila melanogaster and other model organisms used for genetic research. The present study tests for oxidative stress resistance in one set of lines selected for late-life reproduction and extended longevity. Both females and males from the selected lines were appreciably more resistant to oxidative stress than were flies from the control lines. A relative increase in oxidative stress resistance is a correlated response to selection in this laboratory selection experiment. Increased oxidative stress resistance appears to be a relatively robust correlated response to laboratory selection for late-life reproduction and extended longevity.

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Year:  2000        PMID: 10995037     DOI: 10.1093/gerona/55.9.b415

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN: 1079-5006            Impact factor:   6.053


  8 in total

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Authors:  Andrew M Pickering; Marcus Lehr; William J Kohler; Melissa L Han; Richard A Miller
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-07-28       Impact factor: 6.053

Review 2.  T cell replicative senescence in human aging.

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Authors:  Hugo Alves; Anouk Mentink; Bach Le; Clemens A van Blitterswijk; Jan de Boer
Journal:  Tissue Eng Part A       Date:  2013-01-05       Impact factor: 3.845

4.  Atrazine exposure affects longevity, development time and body size in Drosophila melanogaster.

Authors:  Sarah R Marcus; Anthony C Fiumera
Journal:  J Insect Physiol       Date:  2016-06-15       Impact factor: 2.354

5.  Screening for stress-resistance mutations in the mouse.

Authors:  Wallace S Chick; Michael Ludwig; Xiaoyun Zhao; David Kitzenberg; Kristina Williams; Thomas E Johnson
Journal:  Front Genet       Date:  2014-09-08       Impact factor: 4.599

6.  Alfalfa polysaccharide prevents H2O2-induced oxidative damage in MEFs by activating MAPK/Nrf2 signaling pathways and suppressing NF-κB signaling pathways.

Authors:  Lixue Wang; Yuhuai Xie; Weiren Yang; Zaibin Yang; Shuzhen Jiang; Chongyu Zhang; Guiguo Zhang
Journal:  Sci Rep       Date:  2019-02-11       Impact factor: 4.379

Review 7.  Life-History Evolution and the Genetics of Fitness Components in Drosophila melanogaster.

Authors:  Thomas Flatt
Journal:  Genetics       Date:  2020-01       Impact factor: 4.562

8.  Effects of Dual Exposure to the Herbicides Atrazine and Paraquat on Adult Climbing Ability and Longevity in Drosophila melanogaster.

Authors:  Pamela C Lovejoy; Anthony C Fiumera
Journal:  Insects       Date:  2019-11-10       Impact factor: 2.769

  8 in total

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