Literature DB >> 10994810

New cytotoxic agents, BE-52440A and B, produced by a streptomycete.

M Tsukamoto1, S Nakajima, K Murooka, M Naito, H Suzuki, M Hirayama, K Hirano, K Kojiri, H Suda.   

Abstract

New cytotoxic substances, designated BE-52440A and B, were isolated from the mycelium of Streptomyces sp. A52440. The active principles were extracted from the mycelium by methanol and purified by silica gel column chromatography. BE-52440A and B exhibited cytotoxic activity against murine and human tumor cell lines.

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Year:  2000        PMID: 10994810     DOI: 10.7164/antibiotics.53.687

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete.

Authors:  Dagmara K Derewacz; C Ruth McNees; Giovanni Scalmani; Cody L Covington; Ganesh Shanmugam; Lawrence J Marnett; Prasad L Polavarapu; Brian O Bachmann
Journal:  J Nat Prod       Date:  2014-07-21       Impact factor: 4.050

Review 2.  Total synthesis and development of bioactive natural products.

Authors:  Kuniaki Tatsuta
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2008       Impact factor: 3.493

  2 in total

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