Literature DB >> 10993694

Quantitative volumetric analyses of brain magnetic resonance imaging from rat with chronic neuroinflammation.

B Hauss-Wegrzyniak1, J P Galons, G L Wenk.   

Abstract

Brain inflammation may have a pathogenic role in many neurodegenerative diseases, including Alzheimer's disease. In the present study, we investigated the effects of chronic neuroinflammation upon anatomical changes in two regions of interest in the temporal lobe using high-resolution magnetic resonance imaging techniques. We show that chronic infusion of lipopolysaccharide into the fourth ventricle for 4 consecutive weeks enlarged the lateral ventricles and significantly decreased the size of the hippocampal formation and the temporal lobe region. These changes are comparable to those observed in humans during the early stages of Alzheimer's disease. Copyright 2000 Academic Press.

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Year:  2000        PMID： 10993694     DOI： 10.1006/exnr.2000.7469

Source DB:  PubMed          Journal:  Exp Neurol        ISSN： 0014-4886            Impact factor:   5.330


  20 in total

1.  Age-related changes in neural volume and microstructure associated with interleukin-6 are ameliorated by a calorie-restricted diet in old rhesus monkeys.

Authors:  A A Willette; B B Bendlin; D G McLaren; E Canu; E K Kastman; K J Kosmatka; G Xu; A S Field; A L Alexander; R J Colman; R H Weindruch; C L Coe; S C Johnson
Journal:  Neuroimage       Date:  2010-03-15       Impact factor: 6.556

Review 2.  Elevated immune-inflammatory signaling in mood disorders: a new therapeutic target?

Authors:  Robert K McNamara; Francis E Lotrich
Journal:  Expert Rev Neurother       Date:  2012-09       Impact factor: 4.618

3.  Regional brain shrinkage over two years: individual differences and effects of pro-inflammatory genetic polymorphisms.

Authors:  N Persson; P Ghisletta; C L Dahle; A R Bender; Y Yang; P Yuan; A M Daugherty; N Raz
Journal:  Neuroimage       Date:  2014-09-28       Impact factor: 6.556

Review 4.  Inflammation and Alzheimer's disease.

Authors:  H Akiyama; S Barger; S Barnum; B Bradt; J Bauer; G M Cole; N R Cooper; P Eikelenboom; M Emmerling; B L Fiebich; C E Finch; S Frautschy; W S Griffin; H Hampel; M Hull; G Landreth; L Lue; R Mrak; I R Mackenzie; P L McGeer; M K O'Banion; J Pachter; G Pasinetti; C Plata-Salaman; J Rogers; R Rydel; Y Shen; W Streit; R Strohmeyer; I Tooyoma; F L Van Muiswinkel; R Veerhuis; D Walker; S Webster; B Wegrzyniak; G Wenk; T Wyss-Coray
Journal:  Neurobiol Aging       Date:  2000 May-Jun       Impact factor: 4.673

5.  Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients.

Authors:  Kalpana J Kallianpur; Mariana Gerschenson; Brooks I Mitchell; Daniel E LiButti; Tracie M Umaki; Lishomwa C Ndhlovu; Beau K Nakamoto; Dominic C Chow; Cecilia M Shikuma
Journal:  Mitochondrion       Date:  2016-02-23       Impact factor: 4.160

6.  Neuroinflammation alters the hippocampal pattern of behaviorally induced Arc expression.

Authors:  Susanna Rosi; Victor Ramirez-Amaya; Almira Vazdarjanova; Paul F Worley; Carol A Barnes; Gary L Wenk
Journal:  J Neurosci       Date:  2005-01-19       Impact factor: 6.167

7.  Bacterial lipopolysaccharide induces a dose-dependent activation of neuroglia and loss of basal forebrain cholinergic cells in the rat brain.

Authors:  Heidi M Houdek; Jordan Larson; John A Watt; Thad A Rosenberger
Journal:  Inflamm Cell Signal       Date:  2014

Review 8.  In vivo NMR studies of neurodegenerative diseases in transgenic and rodent models.

Authors:  In-Young Choi; Sang-Pil Lee; David N Guilfoyle; Joseph A Helpern
Journal:  Neurochem Res       Date:  2003-07       Impact factor: 3.996

Review 9.  Hypoxia and inflammation in children with sickle cell disease: implications for hippocampal functioning and episodic memory.

Authors:  Mary Iampietro; Tania Giovannetti; Reem Tarazi
Journal:  Neuropsychol Rev       Date:  2014-04-18       Impact factor: 7.444

10.  Mitigation of Inflammation-Induced Mood Dysregulation by Long-Chain Omega-3 Fatty Acids.

Authors:  Robert K McNamara
Journal:  J Am Coll Nutr       Date:  2015       Impact factor: 3.169
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