Literature DB >> 10992517

Differential sensitivities of Chlamydia trachomatis strains to inhibitory effects of gamma interferon.

R P Morrison1.   

Abstract

Gamma interferon (IFN-gamma) is an important cytokine in host defense against chlamydial infection. An in vitro cell culture system was used to show that IFN-gamma inhibition of chlamydial growth, as determined by diminished recovery of infectious elementary bodies, differed markedly among chlamydial strains. These differences in sensitivity among chlamydial strains to IFN-gamma-mediated inhibition may profoundly influence the clinical outcome of infection.

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Year:  2000        PMID： 10992517      PMCID： PMC101569          DOI： 10.1128/IAI.68.10.6038-6040.2000

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  17 in total

1.  Induction of tryptophan catabolism is the mechanism for gamma-interferon-mediated inhibition of intracellular Chlamydia psittaci replication in T24 cells.

Authors:  G I Byrne; L K Lehmann; G J Landry
Journal:  Infect Immun       Date:  1986-08       Impact factor: 3.441

2.  Differentiation of TRIC and LGV organisms based on enhancement of infectivity by DEAE-dextran in cell culture.

Authors:  C Kuo; S Wang; J T Grayston
Journal:  J Infect Dis       Date:  1972-03       Impact factor: 5.226

3.  Role of gamma interferon in controlling murine chlamydial genital tract infection.

Authors:  J I Ito; J M Lyons
Journal:  Infect Immun       Date:  1999-10       Impact factor: 3.441

4.  Amino acid requirements of strains of Chlamydia trachomatis and C. psittaci growing in McCoy cells: relationship with clinical syndrome and host origin.

Authors:  I Allan; J H Pearce
Journal:  J Gen Microbiol       Date:  1983-07

5.  Effect of gamma interferon on resolution of murine chlamydial genital infection.

Authors:  R G Rank; K H Ramsey; E A Pack; D M Williams
Journal:  Infect Immun       Date:  1992-10       Impact factor: 3.441

6.  Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitro.

Authors:  W L Beatty; G I Byrne; R P Morrison
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-01       Impact factor: 11.205

7.  Differential susceptibility of chlamydiae to exogenous fibroblast interferon.

Authors:  G I Byrne; C D Rothermel
Journal:  Infect Immun       Date:  1983-02       Impact factor: 3.441

8.  Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence.

Authors:  W L Beatty; T A Belanger; A A Desai; R P Morrison; G I Byrne
Journal:  Infect Immun       Date:  1994-09       Impact factor: 3.441

9.  Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific, Th1 lymphocyte clone.

Authors:  J U Igietseme; K H Ramsey; D M Magee; D M Williams; T J Kincy; R G Rank
Journal:  Reg Immunol       Date:  1993 Nov-Dec

10.  Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis.

Authors:  H D Caldwell; J Kromhout; J Schachter
Journal:  Infect Immun       Date:  1981-03       Impact factor: 3.441
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  35 in total

Review 1.  Immunity to murine chlamydial genital infection.

Authors:  Richard P Morrison; Harlan D Caldwell
Journal:  Infect Immun       Date:  2002-06       Impact factor: 3.441

Review 2.  New insights into a persistent problem -- chlamydial infections.

Authors:  Richard P Morrison
Journal:  J Clin Invest       Date:  2003-06       Impact factor: 14.808

Review 3.  Chlamydial persistence: beyond the biphasic paradigm.

Authors:  Richard J Hogan; Sarah A Mathews; Sanghamitra Mukhopadhyay; James T Summersgill; Peter Timms
Journal:  Infect Immun       Date:  2004-04       Impact factor: 3.441

4.  Beyond Tryptophan Synthase: Identification of Genes That Contribute to Chlamydia trachomatis Survival during Gamma Interferon-Induced Persistence and Reactivation.

Authors:  Matthew K Muramatsu; Julie A Brothwell; Barry D Stein; Timothy E Putman; Daniel D Rockey; David E Nelson
Journal:  Infect Immun       Date:  2016-09-19       Impact factor: 3.441

Review 5.  Evolution to a chronic disease niche correlates with increased sensitivity to tryptophan availability for the obligate intracellular bacterium Chlamydia pneumoniae.

Authors:  Wilhelmina M Huston; Christopher J Barker; Anu Chacko; Peter Timms
Journal:  J Bacteriol       Date:  2014-03-28       Impact factor: 3.490

Review 6.  Human and Pathogen Factors Associated with Chlamydia trachomatis-Related Infertility in Women.

Authors:  S Menon; P Timms; J A Allan; K Alexander; L Rombauts; P Horner; M Keltz; J Hocking; W M Huston
Journal:  Clin Microbiol Rev       Date:  2015-10       Impact factor: 26.132

7.  Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivo.

Authors:  Anna Roth; Peter König; Ger van Zandbergen; Matthias Klinger; Thomas Hellwig-Bürgel; Walter Däubener; Michael K Bohlmann; Jan Rupp
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-25       Impact factor: 11.205

8.  Interleukin (IL)-2 and IL-12 responses to Chlamydia trachomatis infection in adolescents.

Authors:  C Wang; J Tang; P A Crowley-Nowick; C M Wilson; R A Kaslow; W M Geisler
Journal:  Clin Exp Immunol       Date:  2005-12       Impact factor: 4.330

9.  Serovar-specific immune responses to peptides of variable regions of Chlamydia trachomatis major outer membrane protein in serovar D-infected women.

Authors:  Pragya Srivastava; Rishein Gupta; Hem Chandra Jha; Rajneesh Jha; Apurb Rashmi Bhengraj; Sudha Salhan; Aruna Mittal
Journal:  Clin Exp Med       Date:  2008-09-25       Impact factor: 3.984

10.  Inclusion biogenesis and reactivation of persistent Chlamydia trachomatis requires host cell sphingolipid biosynthesis.

Authors:  D Kesley Robertson; Ling Gu; Regina K Rowe; Wandy L Beatty
Journal:  PLoS Pathog       Date:  2009-11-20       Impact factor: 6.823
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