Literature DB >> 1099200

Antimalarial phenanthrene amino alcohols. 3. Halogen-containing 9-phenanthrenemethanols.

E A Nodiff, A J Saggiomo, K Tanabe, E H Chen, M Shinbo, M P Tyagi, A Kozuka, H Otomasu, B L Verma, D Goff.   

Abstract

A series of new 9-phenanthrene amino alcohols has been prepared in which each compound bears from one to five halogen or halogen-containing moieties. A number of these compounds are extremely active against Plasmodium berghei in the mouse. Some structural requirements for optimal efficacy are considered.

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Year:  1975        PMID: 1099200     DOI: 10.1021/jm00244a012

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  1 in total

1.  Antimalarial activities of various 9-phenanthrenemethanols with special attention to WR-122,455 and WR-171,669.

Authors:  L H Schmidt; R Crosby; J Rasco; D Vaughan
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

  1 in total

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