Literature DB >> 10991422

Scanning probe-based frequency-dependent microrheology of polymer gels and biological cells.

R E Mahaffy1, C K Shih, F C MacKintosh, J Käs.   

Abstract

A new scanning probe-based microrheology approach is used to quantify the frequency-dependent viscoelastic behavior of both fibroblast cells and polymer gels. The scanning probe shape was modified using polystyrene beads for a defined surface area nondestructively deforming the sample. An extended Hertz model is introduced to measure the frequency-dependent storage and loss moduli even for thin cell samples. Control measurements of the polyacrylamide gels compare well with conventional rheological data. The cells show a viscoelastic signature similar to in vitro actin gels.

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Year:  2000        PMID： 10991422     DOI： 10.1103/PhysRevLett.85.880

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN： 0031-9007            Impact factor:   9.161


  114 in total

1.  The optical stretcher: a novel laser tool to micromanipulate cells.

Authors:  J Guck; R Ananthakrishnan; H Mahmood; T J Moon; C C Cunningham; J Käs
Journal:  Biophys J       Date:  2001-08       Impact factor: 4.033

2.  Determination of elastic moduli of thin layers of soft material using the atomic force microscope.

Authors:  Emilios K Dimitriadis; Ferenc Horkay; Julia Maresca; Bechara Kachar; Richard S Chadwick
Journal:  Biophys J       Date:  2002-05       Impact factor: 4.033

3.  Microrheology of human lung epithelial cells measured by atomic force microscopy.

Authors:  Jordi Alcaraz; Lara Buscemi; Mireia Grabulosa; Xavier Trepat; Ben Fabry; Ramon Farré; Daniel Navajas
Journal:  Biophys J       Date:  2003-03       Impact factor: 4.033

4.  Substrate compliance versus ligand density in cell on gel responses.

Authors:  Adam Engler; Lucie Bacakova; Cynthia Newman; Alina Hategan; Maureen Griffin; Dennis Discher
Journal:  Biophys J       Date:  2004-01       Impact factor: 4.033

5.  Quantitative analysis of the viscoelastic properties of thin regions of fibroblasts using atomic force microscopy.

Authors:  R E Mahaffy; S Park; E Gerde; J Käs; C K Shih
Journal:  Biophys J       Date:  2004-03       Impact factor: 4.033

6.  Modeling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in vitro.

Authors:  Jörg Galle; Markus Loeffler; Dirk Drasdo
Journal:  Biophys J       Date:  2004-10-08       Impact factor: 4.033

7.  Tracking mechanics and volume of globular cells with atomic force microscopy using a constant-height clamp.

Authors:  Martin P Stewart; Yusuke Toyoda; Anthony A Hyman; Daniel J Müller
Journal:  Nat Protoc       Date:  2012-01-05       Impact factor: 13.491

8.  Topographic modulation of the orientation and shape of cell nuclei and their influence on the measured elastic modulus of epithelial cells.

Authors:  Clayton T McKee; Vijay K Raghunathan; Paul F Nealey; Paul Russell; Christopher J Murphy
Journal:  Biophys J       Date:  2011-11-01       Impact factor: 4.033

9.  High throughput cell nanomechanics with mechanical imaging interferometry.

Authors:  Jason Reed; Matthew Frank; Joshua J Troke; Joanna Schmit; Sen Han; Michael A Teitell; James K Gimzewski
Journal:  Nanotechnology       Date:  2008-06-11       Impact factor: 3.874

10.  Indentation quantification for in-liquid nanomechanical measurement of soft material using an atomic force microscope: rate-dependent elastic modulus of live cells.

Authors:  Juan Ren; Shiyan Yu; Nan Gao; Qingze Zou
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2013-11-18
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