| Literature DB >> 1099136 |
L R Brown, S Dreizen, S Handler, D A Johnston.
Abstract
A longitudinal study was performed to assess the effects of radiation-induced xerostomia on the human oral microflora. Pronounced microbial population shifts were found in each of five intraoral sites tested. Cariogenic microorganisms gained prominence at the expense of noncariogenic microorganisms in concert with the saliva shutdown. These changes occurred before the onset of clinical caries irrespective of whether or not a topical fluoride gel was used as a caries preventive.Entities:
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Year: 1975 PMID： 1099136 DOI： 10.1177/00220345750540040801
Source DB: PubMed Journal: J Dent Res ISSN： 0022-0345 Impact factor: 6.116