Literature DB >> 10990910

Essential nonlinearities in hearing.

V M Eguíluz1, M Ospeck, Y Choe, A J Hudspeth, M O Magnasco.   

Abstract

Our hearing organ, the cochlea, evidently poises itself at a Hopf bifurcation to maximize tuning and amplification. We show that in this condition several effects are expected to be generic: compression of the dynamic range, infinitely sharp tuning at zero input, and generation of combination tones. These effects are "essentially" nonlinear in that they become more marked the smaller the forcing: there is no audible sound soft enough not to evoke them. All the well-documented nonlinear aspects of hearing therefore appear to be consequences of the same underlying mechanism.

Mesh:

Year:  2000        PMID: 10990910     DOI: 10.1103/PhysRevLett.84.5232

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  87 in total

1.  Putting ion channels to work: mechanoelectrical transduction, adaptation, and amplification by hair cells.

Authors:  A J Hudspeth; Y Choe; A D Mehta; P Martin
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

2.  Compressive nonlinearity in the hair bundle's active response to mechanical stimulation.

Authors:  P Martin; A J Hudspeth
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-27       Impact factor: 11.205

3.  Comparison of a hair bundle's spontaneous oscillations with its response to mechanical stimulation reveals the underlying active process.

Authors:  P Martin; A J Hudspeth; F Jülicher
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-27       Impact factor: 11.205

4.  Physical basis of two-tone interference in hearing.

Authors:  F Jülicher; D Andor; T Duke
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

5.  Evidence of a Hopf bifurcation in frog hair cells.

Authors:  M Ospeck; V M Eguíluz; M O Magnasco
Journal:  Biophys J       Date:  2001-06       Impact factor: 4.033

6.  Push or pull? Teams of motor proteins have it both ways.

Authors:  Thomas Duke
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-14       Impact factor: 11.205

7.  Bidirectional cooperative motion of molecular motors.

Authors:  M Badoual; F Jülicher; J Prost
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-14       Impact factor: 11.205

8.  Negative hair-bundle stiffness betrays a mechanism for mechanical amplification by the hair cell.

Authors:  P Martin; A D Mehta; A J Hudspeth
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

9.  Limiting frequency of the cochlear amplifier based on electromotility of outer hair cells.

Authors:  Mark Ospeck; Xiao-xia Dong; Kuni H Iwasa
Journal:  Biophys J       Date:  2003-02       Impact factor: 4.033

10.  Two adaptation processes in auditory hair cells together can provide an active amplifier.

Authors:  Andrej Vilfan; Thomas Duke
Journal:  Biophys J       Date:  2003-07       Impact factor: 4.033

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