Literature DB >> 10990373

Regulation of the epithelial sodium channel (ENaC) by accessory proteins.

D Rotin1.   

Abstract

The epithelial sodium channel (ENaC) plays a key role in the regulation of fluid absorption in the kidney, lung, colon and exocrine glands, and in the regulation of blood pressure. Abnormal functioning of ENaC is associated with several human diseases, including pseudohypoaldosteronism type I, Liddle's syndrome, pulmonary edema, and cystic fibrosis. ENaC is regulated by several hormones, ions and accessory proteins. This review focuses on the regulation of ENaC by recently described accessory proteins, mainly Nedd4, syntaxin 1A, CFTR, sgk, K-Ras2A and Cap-1.

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Year:  2000        PMID: 10990373     DOI: 10.1097/00041552-200009000-00012

Source DB:  PubMed          Journal:  Curr Opin Nephrol Hypertens        ISSN: 1062-4821            Impact factor:   2.894


  9 in total

Review 1.  Mechanisms of hypertension: the expanding role of aldosterone.

Authors:  E Marie Freel; John M C Connell
Journal:  J Am Soc Nephrol       Date:  2004-08       Impact factor: 10.121

2.  Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC).

Authors:  Michael B Butterworth; Robert S Edinger; Mark R Silvis; Luciana I Gallo; Xiubin Liang; Gerard Apodaca; Raymond A Frizzell; Raymond A Fizzell; John P Johnson
Journal:  Am J Physiol Renal Physiol       Date:  2011-11-30

Review 3.  Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC).

Authors:  Johannes Loffing; Christoph Korbmacher
Journal:  Pflugers Arch       Date:  2009-03-11       Impact factor: 3.657

Review 4.  MicroRNAs and the regulation of aldosterone signaling in the kidney.

Authors:  Michael B Butterworth
Journal:  Am J Physiol Cell Physiol       Date:  2015-02-11       Impact factor: 4.249

5.  Status of fluid and electrolyte absorption in cystic fibrosis.

Authors:  M M Reddy; M Jackson Stutts
Journal:  Cold Spring Harb Perspect Med       Date:  2013-01-01       Impact factor: 6.915

6.  Aldosterone regulates microRNAs in the cortical collecting duct to alter sodium transport.

Authors:  Robert S Edinger; Claudia Coronnello; Andrew J Bodnar; Mariana Labarca; Vivek Bhalla; William A LaFramboise; Panayiotis V Benos; Jacqueline Ho; John P Johnson; Michael B Butterworth
Journal:  J Am Soc Nephrol       Date:  2014-04-17       Impact factor: 10.121

7.  The epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulation.

Authors:  Robert S Edinger; Carol A Bertrand; Christine Rondandino; Gerard A Apodaca; John P Johnson; Michael B Butterworth
Journal:  PLoS One       Date:  2012-09-28       Impact factor: 3.240

Review 8.  Regulation of epithelial sodium transport via epithelial Na+ channel.

Authors:  Yoshinori Marunaka; Naomi Niisato; Akiyuki Taruno; Mariko Ohta; Hiroaki Miyazaki; Shigekuni Hosogi; Ken-Ichi Nakajima; Katsuyuki Kusuzaki; Eishi Ashihara; Kyosuke Nishio; Yoshinobu Iwasaki; Takashi Nakahari; Takahiro Kubota
Journal:  J Biomed Biotechnol       Date:  2011-10-17

9.  Raman micro-spectroscopy as a viable tool to monitor and estimate the ionic transport in epithelial cells.

Authors:  Leonardo Puppulin; Giuseppe Pezzotti; Hongxin Sun; Shigekuni Hosogi; Takashi Nakahari; Toshio Inui; Yasuaki Kumamoto; Hideo Tanaka; Yoshinori Marunaka
Journal:  Sci Rep       Date:  2017-06-13       Impact factor: 4.379

  9 in total

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