Literature DB >> 10990363

Gremlins, glomeruli and diabetic nephropathy.

D W Lappin1, C Hensey, R McMahon, C Godson, H R Brady.   

Abstract

There have been major advances in our understanding of the pathogenetic mechanisms of diabetic nephropathy in recent years. Of particular interest is the emerging paradigm of the role that developmentally important genes may play in this process, representing recapitulation of the ontogenic process. This review examines the potential pathophysiological involvement of one such developmental gene gremlin in diabetic nephropathy.

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Year:  2000        PMID: 10990363     DOI: 10.1097/00041552-200009000-00002

Source DB:  PubMed          Journal:  Curr Opin Nephrol Hypertens        ISSN: 1062-4821            Impact factor:   2.894


  8 in total

1.  A GREM1 gene variant associates with diabetic nephropathy.

Authors:  Amy Jayne McKnight; Christopher C Patterson; Kerry A Pettigrew; David A Savage; Jill Kilner; Madeline Murphy; Denise Sadlier; Alexander P Maxwell
Journal:  J Am Soc Nephrol       Date:  2010-02-11       Impact factor: 10.121

2.  Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County, Texas.

Authors:  Yi-Ping Fu; D Michael Hallman; Victor H Gonzalez; Barbara E K Klein; Ronald Klein; M Geoffrey Hayes; Nancy J Cox; Graeme I Bell; Craig L Hanis
Journal:  J Ophthalmol       Date:  2010-09-02       Impact factor: 1.909

3.  Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion.

Authors:  Minsoo Kim; Soomin Yoon; Sukmook Lee; Seon Ah Ha; Hyun Kee Kim; Jin Woo Kim; Junho Chung
Journal:  PLoS One       Date:  2012-04-13       Impact factor: 3.240

4.  The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein.

Authors:  Hong Namkoong; Seung Min Shin; Hyun Kee Kim; Seon-Ah Ha; Goang Won Cho; Soo Young Hur; Tae Eung Kim; Jin Woo Kim
Journal:  BMC Cancer       Date:  2006-03-18       Impact factor: 4.430

5.  Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease.

Authors:  Lucy M Hinder; Meeyoung Park; Amy E Rumora; Junguk Hur; Felix Eichinger; Subramaniam Pennathur; Matthias Kretzler; Frank C Brosius; Eva L Feldman
Journal:  J Cell Mol Med       Date:  2017-03-08       Impact factor: 5.310

6.  Altered Expression of Long Noncoding and Messenger RNAs in Diabetic Nephropathy following Treatment with Rosiglitazone.

Authors:  Liwen Zhang; Ying Zhou; Fangfang Zhou; Xialian Yu; Jian Liu; Yunzi Liu; Yufei Zhu; Weiming Wang; Nan Chen
Journal:  Biomed Res Int       Date:  2020-01-14       Impact factor: 3.411

7.  Epigenetic Modulation of Gremlin-1/NOTCH Pathway in Experimental Crescentic Immune-Mediated Glomerulonephritis.

Authors:  Lucia Tejedor-Santamaria; Jose Luis Morgado-Pascual; Laura Marquez-Exposito; Beatriz Suarez-Alvarez; Raul R Rodrigues-Diez; Antonio Tejera-Muñoz; Vanessa Marchant; Sergio Mezzano; Carlos Lopez-Larrea; Anna Sola; Gema Maria Fernandez-Juarez; Alberto Ortiz; Sandra Rayego-Mateos; Marta Ruiz-Ortega
Journal:  Pharmaceuticals (Basel)       Date:  2022-01-20

Review 8.  Research Progress on the Pathological Mechanisms of Podocytes in Diabetic Nephropathy.

Authors:  Lili Zhang; Zhige Wen; Lin Han; Yujiao Zheng; Yu Wei; Xinmiao Wang; Qing Wang; Xinyi Fang; Linhua Zhao; Xiaolin Tong
Journal:  J Diabetes Res       Date:  2020-07-08       Impact factor: 4.011

  8 in total

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