Literature DB >> 10989861

Fulminant pulmonary edema after intramuscular ketamine.

C K Pandey1, N Mathur, N Singh, H C Chandola.   

Abstract

PURPOSE: To report an unusual case of pulmonary edema following intramuscular ketamine administration. CLINICAL FEATURES: An eight-year-old, healthy girl presented for dressing of first degree burns on dorsum of hand. Ten minutes after administration of 125 mg ketamine im, she developed laboured breathing, cyanosis, and bilateral crepitations and arterial blood gas analysis showed PaO2 55 mmHg. There was no evidence of upper airway obstruction. On intubating the trachea, pink frothy fluid emerged from the tube. She was diagnosed as a case of neurogenic pulmonary edema. She was managed with positive pressure ventilation with positive end expiratory pressure, morphine and furosemide. With this treatment she showed a favourable recovery.
CONCLUSION: Ketamine was given im to aid burns dressing in this case because it has distinct advantages above the other anesthetic agents including that of being a good analgesic which is absorbed by im route. Its use led to the development of pulmonary edema.

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Year:  2000        PMID: 10989861     DOI: 10.1007/BF03019671

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   5.063


  4 in total

1.  Crisis management during anaesthesia: pulmonary oedema.

Authors:  M J Chapman; J A Myburgh; M T Kluger; W B Runciman
Journal:  Qual Saf Health Care       Date:  2005-06

2.  Ketamine and pulmonary oedema-report of two cases.

Authors:  S Parthasarathy; M Ravishankar; S Selvarajan; T Anbalagan
Journal:  Indian J Anaesth       Date:  2009-08

3.  Ketamine inhibits lung fluid clearance through reducing alveolar sodium transport.

Authors:  Yong Cui; Hongguang Nie; Hong Ma; Lei Chen; Lin Zhang; Junke Wang; Honglong Ji
Journal:  J Biomed Biotechnol       Date:  2011-10-03

4.  The epidemiology and patterns of acute and chronic toxicity associated with recreational ketamine use.

Authors:  Sarbjeet S Kalsi; David M Wood; Paul I Dargan
Journal:  Emerg Health Threats J       Date:  2011-04-15
  4 in total

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