Literature DB >> 1098765

Proliferation-dependent cytotoxicity of anticancer agents: a review.

F Valeriote, L van Putten.   

Abstract

One of the factors of importance in determining the killing of mammalian cells following exposure to a variety of anticancer agents is the proliferative state of the cell population. Generally, proliferating cells are much more sensitive to anticancer agents than are nonproliferating cells. In this review, the cellular aspects of this differential sensitivity are discussed with the hemopoietic stem cell population and tissue culture cells as the focus for the analysis. This phenomenon is not only of concern to the cell biologist but also has implications with regard to scheduling of anticancer agents against human tumors.

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Year:  1975        PMID： 1098765

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  55 in total

1.  Cell fusion to study nuclear-cytoplasmic interactions in endothelial cell apoptosis.

Authors:  V A Polunovsky; D H Ingbar; M Peterson; P B Bitterman
Journal:  Am J Pathol       Date:  1996-07       Impact factor: 4.307

2.  Reduced variation in the clonogenic assay obtained by standardization of the cell culture conditions prior to drug testing on human small cell lung cancer cell lines.

Authors:  P B Jensen; H Roed; L Vindeløv; I J Christensen; H H Hansen
Journal:  Invest New Drugs       Date:  1989-11       Impact factor: 3.850

3.  Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells.

Authors:  Kavitha Sivasubramaniyan; Abhishek Harichandan; Karin Schilbach; Andreas F Mack; Jens Bedke; Arnulf Stenzl; Lothar Kanz; Gerhard Niederfellner; Hans-Jörg Bühring
Journal:  Glycobiology       Date:  2015-05-15       Impact factor: 4.313

4.  Nutrient-Dependent Efficacy of the Antifungal Protein YvgO Correlates to Cellular Proliferation Rate in Candida albicans 3153A and Byssochlamys fulva H25.

Authors:  David C Manns; John J Churey; Randy W Worobo
Journal:  Probiotics Antimicrob Proteins       Date:  2014-12       Impact factor: 4.609

5.  Combination therapy induces unfolded protein response and cytoskeletal rearrangement leading to mitochondrial apoptosis in prostate cancer.

Authors:  Sandeep Kumar; Ajay K Chaudhary; Rahul Kumar; Jordan O'Malley; Anna Dubrovska; Xinjiang Wang; Neelu Yadav; David W Goodrich; Dhyan Chandra
Journal:  Mol Oncol       Date:  2016-03-31       Impact factor: 6.603

6.  Effect of some cytostatics on the haemopoietic stem cells (CFUs) in blood.

Authors:  E Necas; P Ponka; J Neuwirt
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

7.  Stage 2 combination testing of rapamycin with cytotoxic agents by the Pediatric Preclinical Testing Program.

Authors:  Peter J Houghton; Christopher L Morton; Richard Gorlick; Richard B Lock; Hernan Carol; C Patrick Reynolds; Min H Kang; John M Maris; Stephen T Keir; E Anders Kolb; Jianrong Wu; Amy W Wozniak; Catherine A Billups; Larry Rubinstein; Malcolm A Smith
Journal:  Mol Cancer Ther       Date:  2010-01-06       Impact factor: 6.261

8.  Tumor cell growth fraction in Hodgkin's disease.

Authors:  J Gerdes; J Van Baarlen; S Pileri; R Schwarting; J A Van Unnik; H Stein
Journal:  Am J Pathol       Date:  1987-09       Impact factor: 4.307

Review 9.  Tumor hypoxia: its impact on cancer therapy.

Authors:  J E Moulder; S Rockwell
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

10.  Morphological changes in anaplastic gliomas treated with radiation and chemotherapy.

Authors:  L Gerstner; K Jellinger; W D Heiss; G Wöber
Journal:  Acta Neurochir (Wien)       Date:  1977       Impact factor: 2.216
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