| Literature DB >> 10987416 |
T A Miller1, J Ghosh, C E Myers, T L Macdonald.
Abstract
The synthesis and assessment of the mitogenic properties of 5-HETE congeners are reported. These studies represent an effort to develop a structure-activity profile for ligands of the 5-HETE/5-oxoETE G-protein coupled receptor(s). Many of these agents possess mitogenic activity that equals or exceeds that of racemic 5-HETE family constituents in prostate cancer cell lines.Entities:
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Year: 2000 PMID： 10987416 DOI： 10.1016/s0960-894x(00)00370-x
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823