Use of electron beam tomography to quantify cardiac diastolic function.

The examples provided in this article indicate that EBT, in addition to allowing for detailed descriptions of cardiac anatomy and contraction characteristics in man, can also be used to evaluate global and regional LV diastolic function using an approach previously validated for applications in radionuclide angiography. EBT is an established imaging modality that has been shown to be highly applicable to quantitative determination of ventricular mass, RV and LV volumes, and global and regional ventricular systolic and diastolic function in a variety of cardiac pathologic states. The attractiveness of EBT lies not so much in a single determination of systolic function or diastolic filling in a given individual, but in the strength of an easily acquired, highly reproducible, and accurate serial imaging method in patients following pharmacologic or interventional therapy for a specific cardiac disease.