Literature DB >> 10986204

Specific targeting of IL-6 signalling pathway: a new way to treat IBD?

P Desreumaux1.   

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Year:  2000        PMID: 10986204      PMCID: PMC1728094          DOI: 10.1136/gut.47.4.465

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


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  11 in total

1.  Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance.

Authors:  K Ina; J Itoh; K Fukushima; K Kusugami; T Yamaguchi; K Kyokane; A Imada; D G Binion; A Musso; G A West; G M Dobrea; T S McCormick; E G Lapetina; A D Levine; C A Ottaway; C Fiocchi
Journal:  J Immunol       Date:  1999-07-15       Impact factor: 5.422

2.  IL-6 is required for the development of Th1 cell-mediated murine colitis.

Authors:  M Yamamoto; K Yoshizaki; T Kishimoto; H Ito
Journal:  J Immunol       Date:  2000-05-01       Impact factor: 5.422

3.  IL-6 rescues resting mouse T cells from apoptosis.

Authors:  T K Teague; P Marrack; J W Kappler; A T Vella
Journal:  J Immunol       Date:  1997-06-15       Impact factor: 5.422

4.  Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.

Authors:  R Atreya; J Mudter; S Finotto; J Müllberg; T Jostock; S Wirtz; M Schütz; B Bartsch; M Holtmann; C Becker; D Strand; J Czaja; J F Schlaak; H A Lehr; F Autschbach; G Schürmann; N Nishimoto; K Yoshizaki; H Ito; T Kishimoto; P R Galle; S Rose-John; M F Neurath
Journal:  Nat Med       Date:  2000-05       Impact factor: 53.440

5.  Preliminary evaluation of safety and activity of recombinant human interleukin 11 in patients with active Crohn's disease.

Authors:  B E Sands; S Bank; C A Sninsky; M Robinson; S Katz; J W Singleton; P B Miner; M A Safdi; S Galandiuk; S B Hanauer; G W Varilek; A L Buchman; V D Rodgers; B Salzberg; B Cai; J Loewy; M F DeBruin; H Rogge; M Shapiro; U S Schwertschlag
Journal:  Gastroenterology       Date:  1999-07       Impact factor: 22.682

6.  IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice.

Authors:  D Aderka; J M Le; J Vilcek
Journal:  J Immunol       Date:  1989-12-01       Impact factor: 5.422

7.  Soluble interleukin-6 receptors in inflammatory bowel disease: relation to circulating interleukin-6.

Authors:  K Mitsuyama; A Toyonaga; E Sasaki; O Ishida; H Ikeda; O Tsuruta; K Harada; H Tateishi; T Nishiyama; K Tanikawa
Journal:  Gut       Date:  1995-01       Impact factor: 23.059

8.  Evidence for continuous stimulation of interleukin-6 production in Crohn's disease.

Authors:  V Gross; T Andus; I Caesar; M Roth; J Schölmerich
Journal:  Gastroenterology       Date:  1992-02       Impact factor: 22.682

9.  Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells.

Authors:  M Rincón; J Anguita; T Nakamura; E Fikrig; R A Flavell
Journal:  J Exp Med       Date:  1997-02-03       Impact factor: 14.307

10.  Defective inflammatory response in interleukin 6-deficient mice.

Authors:  E Fattori; M Cappelletti; P Costa; C Sellitto; L Cantoni; M Carelli; R Faggioni; G Fantuzzi; P Ghezzi; V Poli
Journal:  J Exp Med       Date:  1994-10-01       Impact factor: 14.307

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  4 in total

Review 1.  Crohn's Disease: Evolution, Epigenetics, and the Emerging Role of Microbiome-Targeted Therapies.

Authors:  Ersilia M DeFilippis; Randy Longman; Michael Harbus; Kyle Dannenberg; Ellen J Scherl
Journal:  Curr Gastroenterol Rep       Date:  2016-03

Review 2.  Cellular Immune Signal Exchange From Ischemic Stroke to Intestinal Lesions Through Brain-Gut Axis.

Authors:  Zizhao Yang; Fei Wei; Bin Zhang; Yun Luo; Xiaoyan Xing; Min Wang; Rongchang Chen; Guibo Sun; Xiaobo Sun
Journal:  Front Immunol       Date:  2022-04-01       Impact factor: 8.786

3.  Lactobacillus plantarum MYL26 induces endotoxin tolerance phenotype in Caco-2 cells.

Authors:  Yi-Heng Chiu; Ying-Chen Lu; Chu-Chyn Ou; Shiao-Lin Lin; Chin-Chi Tsai; Chien-Tsai Huang; Meei-Yn Lin
Journal:  BMC Microbiol       Date:  2013-08-10       Impact factor: 3.605

Review 4.  Immunogenic Effect of Hyperthermia on Enhancing Radiotherapeutic Efficacy.

Authors:  Sungmin Lee; Beomseok Son; Gaeul Park; Hyunwoo Kim; Hyunkoo Kang; Jaewan Jeon; HyeSook Youn; BuHyun Youn
Journal:  Int J Mol Sci       Date:  2018-09-17       Impact factor: 5.923

  4 in total

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