Literature DB >> 10986099

First total synthesis of dragmacidin A via indolylglycines.

T Kawasaki1, H Enoki, K Matsumura, M Ohyama, M Inagawa, M Sakamoto.   

Abstract

The first total synthesis of dragmacidin A has been accomplished using condensation of two indolylglycines followed by cyclization and reduction. The general and practical method for synthesis of indolylglycines via Wittig reaction, azide addition, and reduction from indolin-3-ones is also described.

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Year:  2000        PMID: 10986099     DOI: 10.1021/ol006394g

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Total Synthesis of (±)-Dragmacidin E: Problems Solved and Lessons Learned.

Authors:  Ken S Feldman; Paiboon Ngernmeesri
Journal:  Synlett       Date:  2012-08       Impact factor: 2.454

2.  Dragmacidin E synthesis studies. Preparation of a model heptacyclic core structure.

Authors:  Ken S Feldman; Paiboon Ngernmeesri
Journal:  Org Lett       Date:  2010-10-15       Impact factor: 6.005

3.  Synthesis of a cyclic pentapeptide mimic of the active site His-Tyr cofactor of cytochrome c oxidase.

Authors:  Maximillian E Mahoney; Allen Oliver; Olöf Einarsdóttir; Joseph P Konopelski
Journal:  J Org Chem       Date:  2009-11-06       Impact factor: 4.354

4.  Efficient one-pot synthesis of indol-3-yl-glycines via uncatalyzed Friedel-Crafts reaction in water.

Authors:  Mehdi Ghandi; Abuzar Taheri
Journal:  Molecules       Date:  2009-03-05       Impact factor: 4.411

  4 in total

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